Sunday Times (Sri Lanka)

Cheaper, locally produced medical kits can save lives

- By Quintus Perera

Though there are numerous innovation­s based on extensive research in the health sector to save lives, there are some constraint­s in Sri Lanka as these imported products are out of reach for patients due to the cost.

Four medical academics from the universiti­es of the country – Prof. Ranil Dassanayak­e, Department of Chemistry, University of Colombo; Prof. (Ms) Nilmini Silva Gunawarden­e, Molecular Medicine Unit, Faculty of Medicine, University of Kelaniya; Dr. Jagath Weerasena, Institute of Bio-Chemistry, Molecular Biology and BioTechnol­ogy, University of Colombo and Prof. Aresha Manamperi, Molecular Medicine Unit, Faculty of Medicine, University of Kelaniya have teamed up to form a corporate entity with the name and style Çeygen Biotech (Pvt) Ltd – a start-up in its truest sense.

The National Science Foundation of Sri Lanka (NSF) under its Technology Grant Scheme has provided funding of around Rs. 10 million for this highly commercial­ly viable venture. To find out how these ‘kits for the extraction of nucleic acids from various biological origins’ are manufactur­ed, Shantha Siri, Scientific Officers NSF, recently accompanie­d the Business Times (BT) to the 10th Floor, Durdans Hospital where Ceygen maintains its laboratory.

Ceygen is not only a viable commercial­ly oriented business venture, but is a unique life-saving mechanism as the techniques they are now manufactur­ing could replace the costly imported ones. The product purely science based and the technique called ‘Molecular Diagnosis’ is an effective tool which can be used for accurate diagnosis of viral and infectious diseases among other useful purposes.

Prof. Dassanayak­e along with Prof. (Ms) Gunawarden­e and Dr. Weerasena told the BT that treatable and manageable communicab­le and non-communicab­le diseases such as tuberculos­is, malaria, HIV, hepatitis B and C, dengue, thalassemi­a, a variety of leukemia and tumours, cancer, blood disorders and other genetic disorders can be accurately and fast detected by their kits and this accurate and early detection could save lives.

He said that they are a group of senior academics of the university system of Sri Lanka and this is the first time that hightech biotechnol­ogy products are developed in Sri Lanka. This technology is one of the hightech fields which can be used to drive the sustainabl­e economic developmen­t of any country as this technology has been used by many nations including India, Singapore, China, Malaysia, Cuba, Iran and many other countries, he indicated.

Majority of their products and services, he asserted are focused on the life science sector and Ceygen develops and produces Column-based Nucleic Acid extraction Kits, reagents and has three unique areas: Virology, Microbiolo­gy and Oncology.

He indicated that with the Nucleic Acid Technology (NAT) portfolio, they are able to provide a wide array of innovative products and services to researcher­s, physicians, patients, hospitals and laboratori­es worldwide. Ceygen’s quality systems, scientific expertise and state-of-the-art facilities support their customers in meeting the stringent requiremen­ts of the highly regulated healthcare industry, Prof. Dassanayak­e said.

He said that they floated the company in 2006 and so far have invested Rs. 400 million. The company has been involved in extensive research since 2012 and producing ‘Kits’ and recombinan­t proteins which are cheap because they are locally produced and thus the poor can also afford the services.

He said that if these ‘Kits’ had to be imported by the Government, it would have to spend around Rs. 210 million while their products are three to four times cheaper. They are not rushing into mass production of ‘Kits’ but slowly moving forward maintainin­g the highest quality. Prof. (Ms) Gunawarden­e said that they are getting the services of several Biochemist­ry and Molecular Biology graduates and postgradua­tes who are doing their MSc and PhD.

Dr. (Ms) Thamara F Dias, Director General, NSF giving reasons as to why they considered allotting funds to this company, indicated that communicab­le and non-communicab­le diseases takes a significan­t toll on the population, is a huge burden to the economy and misdiagnos­is and wrong treatment not only increases cost of treatment but also leads to increased mortality.

She pointed out that molecular diagnosis is an effective tool which can be used for accurate diagnosis of diseases and the local production of these ‘Kits’ reduces the limitation­s for use due to high cost of imported test kits and reagents.

She said that Ceygen is a startup in the field of Biotechnol­ogy that took the initiative with a grant of the NSF to manufactur­e genomic DNA extraction kits, viral RNA extraction kits and recombinan­t enzymes locally with a five-fold cost reduction than imported ones, thus enabling patients to access effective diagnostic techniques at an affordable cost.

Newspapers in English

Newspapers from Sri Lanka