Sunday Times (Sri Lanka)

Our commonalit­y is gene-deep

Following a recent study that revealed that the Sinhalese and Sri Lankan Tamils share a common genetic ancestry and one that can be traced back to West Eurasian (Iranian) and not South Asian, Kumudini Hettiarach­chi speaks to Dr. Ruwandi Ranasinghe, one of

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We, both the Sinhalese and the Sri Lankan Tamils, are truly ‘unique’ and share a common genetic ancestry!

This common genetic ancestry has been revealed in a recent scientific study based on irrefutabl­e evidence, busting many a myth and debunking numerous speculatio­n.

“It goes beyond or supersedes the borders of different ethnicitie­s, the different languages that the two groups speak and also their different cultural

practices,” says scientist

Dr. Ruwandi Ranasinghe of the Colombo University’s Institute of Biochemist­ry, Molecular Biology and Biotechnol­ogy (IBMBB).

Dr. Ranasinghe with the major support of former IBMBB Director Emeritus Prof. Kamani H. Tennekoon has been engaging in genetic studies to reconstruc­t the population history of the Sinhalese and the Sri Lankan Tamils. These studies are being conducted in collaborat­ion with colleagues from India, Dr. Niraj Rai of the Birbal Sahni Institute of Palaeoscie­nces, Lucknow and Prof. Gyaneshwer Chaubey of the Banaras Hindu University, Varanasi.

“The genetic links of both the Sinhalese and the Sri Lankan Tamils are West Eurasian rather than South Asian,” she says.

‘West Eurasian’ simply means that the ‘phylo-geographic’ variation of the Sinhalese and the Sri Lankan Tamils is

of African-Arabian and thus Iranian origin. This differs from theories and beliefs that the Sinhalese and the Sri Lankan Tamils are of South Asian origin, even though the Sri Lankan Tamils have a “minor” southern Indian genetic component.

‘Phylo-geography’ is the study of the historical processes that may be responsibl­e for the past-to-present geographic distributi­ons of genealogic­al lineages, says Dr. Ranasinghe.

Another major revelation is that the Sinhalese have a stronger genetic link to north India and not south

India. The studies have also found that the traces of common roots of the Sinhalese are more on the western side of the Indian subcontine­nt rather than the eastern side.

“These roots are with the Marathas and not so much with the Bengalis,” says Dr. Ranasinghe, going back in history to explain that the Marathas were a Marathi-speaking warrior group from the western Deccan Plateau, which is now Maharashtr­a.

The study participan­ts were Sinhalese (nine in the age-group 18-60 years) from around Colombo and Sri Lankan Tamils of Jaffna origin (four in the age group 18-60 years) but living in

Colombo. There were also participan­ts from different ethnicitie­s from some population­s living in India.

Pointing out that the three-generation rule (having no mixed marriages going back three generation­s) was observed when collecting blood samples and no individual­s were each other's blood relatives, Dr. Ranasinghe says that although the sample size is low for intra-population and genomic selection type studies, they are sufficient for inter-population comparison and understand­ing of population history.

Having taken blood samples from the study participan­ts, the scientists had used a commercial­ly-available analysis chip to run the DNA (deoxyribon­ucleic acid) extracted from the blood samples. DNA is made up of chromosome­s and genes (which determine the inherited physical traits of a person)

Chromosome­s, spaghetti-like structures, come in matching sets of two (or pairs), with hundreds of genes on just

one chromosome. A human cell nucleus contains 46 individual chromosome­s or 23 pairs, half from the mother and the other half from the father.

Dipping into the technicali­ties of the study, she says that they are poring over microscope­s to study the polymorphi­sm array amounting to 500,000 of a single nucleotide variation in the human genome. This test – a single nucleotide polymorphi­sm array (SNP) – looks at a genomic variant at a single base position in the DNA.

Getting back to language, Dr. Ranasinghe says that the Sinhalese speak the Indo-European language of the Indo-Iranian branch, which is said to originate in northweste­rn India, going back to at least the 5th century B.C. Previous genetic studies on low-resolution markers failed to infer the genomic history of the Sinhalese and as such they performed a high-resolution finegraine­d genetic study.

These studies are ongoing to sequence the whole genome of the Sinhalese and the Sri Lankan Tamils, with the addition of the Veddahs as well.

 ?? ?? A map showing the locations of the study samples and the distributi­on of language groups in Sri Lanka and India. (STU is for Sri Lankan Tamils)
A map showing the locations of the study samples and the distributi­on of language groups in Sri Lanka and India. (STU is for Sri Lankan Tamils)
 ?? ?? A comparison of maternal ancestry components among population­s in Sri Lanka and South India.
A comparison of maternal ancestry components among population­s in Sri Lanka and South India.
 ?? ?? Dr. Ruwandi Ranasinghe at work in the lab
Dr. Ruwandi Ranasinghe at work in the lab
 ?? ?? Emeritus Prof. Kamani H. Tennekoon
Emeritus Prof. Kamani H. Tennekoon
 ?? ?? Prof. Gyaneshwer Chaubey
Prof. Gyaneshwer Chaubey
 ?? ?? Dr. Ruwandi Ranasinghe
Dr. Ruwandi Ranasinghe
 ?? ?? Dr. Niraj Rai
Dr. Niraj Rai

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