What is proge­ria?

Friday - - Society -

Hutchin­son-Gil­ford proge­ria syn­drome, more com­monly known as proge­ria, is a ge­netic con­di­tion char­ac­terised by dra­matic, rapid ap­pear­ance of signs of age­ing be­gin­ning in childhood. By 12 months, symp­toms such as slow growth and hair loss be­gin to ap­pear. Pa­tients also find it hard to gain weight.

Af­fected chil­dren de­velop a typ­i­cal fa­cial ap­pear­ance in­clud­ing prom­i­nent eyes, thin nose and lips, a small chin and pro­trud­ing ears. Joint ab­nor­mal­i­ties are also com­mon.

Proge­ria does not dis­rupt in­tel­lec­tual de­vel­op­ment of the child or the de­vel­op­ment of mo­tor skills such as stand­ing and walk­ing.

It isn’t hered­i­tary. Ex­perts say it’s due to a rare gene change, which hap­pens purely by chance.

Chil­dren who suf­fer from proge­ria are ge­net­i­cally sus­cep­ti­ble to pre­ma­ture pro­gres­sive heart disease such as har­den­ing of the ar­ter­ies (ar­te­rioscle­ro­sis) and nearly all proge­ria pa­tients die from heart con­di­tions. They also of­ten suf­fer from symp­toms typ­i­cally seen in much older peo­ple such as stiff­ness of joints.

The life ex­pectancy for a child with proge­ria is about 13, but some with the con­di­tion die younger and some live 20 years or longer.

In ex­tremely rare cases, more than one child in the same fam­ily may have the con­di­tion. There’s no cure for proge­ria.

Source: med­i­cal web­sites

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