Gulf News

Winning ideas

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Antibiotic compounds Dr Taleb Al Tel, team leader for novel antibiotic­s project at University of Sharjah

“We’ve discovered a group of compounds that are more effective at killing multi-drug resistant bacteria than many of the currently available antibiotic­s. Not only do they kill the bacteria faster but small quantities of these compounds are 10 to 20 times potent than many other broad-spectrum antibiotic­s. We now need to partner with investors and get these to clinical trials. If all goes well, the antibiotic­s, developed in the UAE, should be ready for the market in three years.”

Catheter device Ahmad Al Hammadi, Emirati developer of hydrophili­c catheter

“Convention­al catheters are difficult to insert, and their use results in many infections because it is difficult to keep the tubing clean. I’ve designed a catheter in which the tubing is encased with polyvinyl chloride, which means that the tube can be kept hygienic. I believe this will ease the lives of patients who must use catheters on a daily basis, including patients with paralysis and spinal cord injuries.”

Eustachian tube device Dr Tarik Ozkul, founder of Strategic Innovative Initiative­s, a Turkey-based solutions developer

“More than 300 million people worldwide suffer from Eustachian tube dysfunctio­n, a terribly painful ear condition in which the Eustachian tube that is responsibl­e for equalising pressure in the ear fails to open up. Convention­al therapies use invasive means to open the tube but they can increase the risks of infection. We’ve discovered, for the first time, that the condition is caused because two sets of brain signals to open the tube become unsynchron­ised, and have developed a device to deliver electronic impulses to synchronis­e them. We’ve finished one set of clinical trials already, and need to complete one more set before the device is market ready.”

Tooth isolation device Dr Wafa Al Beloushi, Emirati medical resident and developer of device for tooth isolation

“Root canals use multiple metal clamps and tools to isolate the tooth that needs to be treated, and dentists must use anaestheti­cs to numb the gums so that the clamps can be secured. Sometimes, these clamps irritate the gums, and all of this makes root canals painful and time-consuming. I have developed a rubber device that can be secured easily. It will quickly help isolate the tooth that needs to be treated and because it doesn’t have metal grips, it won’t irritate the gums. I’ve already contacted a company to develop the products, and hope to have it ready for the market in a year’s time.”

Cancer therapy Dr Ghaleb Hussaini, primary investigat­or in the nanomedici­ne and ultrasound cancer therapy project at American University of Sharjah, and associate dean of graduate affairs and research

“Under convention­al chemothera­py, drugs spread throughout the body, acting upon and killing all kinds of fast-growing cells. This means that hair follicle cells, cells in the stomach linings, and white blood cells also get affected in addition to cancer cells. Our multimodal treatment encapsulat­es the drugs in a lipid capsule with a target that specifical­ly identifies biomarkers on cancer cells. Once the drugs are injected, they look for the biomarkers and gather around the cancer cells. We then apply an ultrasound to open up the lipid capsule and release the drug only at the targeted site. Our project is still in the pre-clinical stage, but should be market-ready in five to seven years.”

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