S. African child becomes third HIV infected to go into remission
london — A South African child born with HIV has surprised experts by appearing to be effectively cured of the Aids virus after just a year of treatment followed by eight and a half years drug-free.
The child is world’s third one born with HIV to go into remission.
Patients with HIV would normally need to stay on antiretroviral (ART) drugs for the rest of their lives to keep Aids at bay. But this child, still off treatment and now almost 10 years old, has no signs of the disease.
This and other recent, isolated cases of remission have given additional hope to the 37 million people worldwide infected with the virus that causes Aids.
Yet experts urged caution, saying the case is extremely rare and does not suggest a simple path to a cure. “It’s a case that raises more questions than it necessarily answers,” said Linda-Gail Bekker, president of the International Aids Society (IAS), which is holding a conference in Paris this week. “It does raise the interesting notion that maybe treatment isn’t for life. (But) it’s clearly a rare phenomenon.”
The child, whose name and gender were not disclosed, was part of a clinical trial in which researchers were investigating the effect of treating HIV-positive babies in the first few weeks of life, and then stopping and starting the ART medicines whilst checking whether their HIV was being controlled.
The UN said 19.5 million people — more than half of the 37 million patients with HIV — are now on treatment. The vast majority of patients with HIV suffer an increase in the amount of the virus circulating in the body if they stop treatment, but this child was different, the South African researchers said. “To our knowledge, this is the first case of sustained virological control from a randomised trial of ART interruption following early treatment of infants,” they said in a summary of findings presented on Monday.The baby contracted HIV from its mother. Treatment with ART started when it was almost nine weeks old but was interrupted at 40 weeks when the virus had been suppressed. —