Birmingham Post

Statins significan­tly lower rates of breast cancer, study finds

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THERE is a “strong indication” that taking statins is linked to lower rates of breast cancer, claims Birmingham researcher­s.

A 14-year study of more than one million women found those with high cholestero­l were 45 per cent less likely to develop the illness, while the mortality rate of sufferers with high cholestero­l was 40 per cent less.

Dr Rahul Potluri, of Aston Medical School in Birmingham, said: “If a diagnosis of high cholestero­l leads to lower breast cancer rates this must either relate to something inherent in the condition or affected patients, or more likely, to treatment with widely used cholestero­l-lowering interventi­ons such as statins.”

Lead author Dr Paul Carter, of Aston University, said: “Women with a diagnosis of high cholestero­l have strikingly lower rates of breast cancer with improved death rates and survival.

“This gives a strong indication that statins produce this protective effect in breast cancer.”

The link between high cholestero­l and low incidence of breast cancer has been “fascinatin­g

Women with a diagnosis of high cholestero­l have strikingly lower rates of breast cancer Dr Paul Carter, of Aston University

researcher­s for to Dr Potluri.

He said: “This is the most conclusive and direct evidence as yet to confirm the link... showing that patients with high cholestero­l have a lower risk of developing breast cancer and subsequent mortality in a longitudin­al study like this provides the strongest evidence for a protective effect, which is likely related to statins.”

He added: “I don’t think at the moment we can give statins to prevent or reduce mortality from breast cancer per se. But a positive result in a clinical trial could change this and it is an exciting and rapidly progressin­g field.” years” according

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