Burton Mail

US vaccine could be in UK by spring

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A “TREMENDOUS­LY exciting” US coronaviru­s vaccine that may offer very high levels of protection against Covid-19 could arrive in the UK as early as next spring, the Government has said.

British scientists have hailed the news that US firm Moderna’s jab may be 94.5% effective against the illness.

Interim data suggests the jab is highly effective in preventing people getting ill and may work across all age groups, including the elderly.

The UK has already secured 40 million doses of a vaccine from Pfizer/biontech, which uses the same technology as Moderna and should be in the UK before Christmas.

A Government spokesman said: “The news from Moderna appears to be good and represents another significan­t step towards finding an effective Covid-19 vaccine.

“As part of the ongoing work of the Vaccines Taskforce, the Government is in advanced discussion­s with Moderna to ensure UK access to their vaccine as part of the wider UK portfolio. Moderna are currently scaling up their European supply chain which means these doses would become available in spring 2021 in the UK at the earliest.”

Scientists said the news bodes well for other Covid-19 vaccines, with the one for Oxford University and UK pharmaceut­ical giant Astrazenec­a due to report in the coming days or weeks.

Moderna intends to submit an applicatio­n for an emergency use authorisat­ion with the US Food and Drug Administra­tion shortly and will submit further data on the vaccine’s effectiven­ess and safety.

The firm’s final-stage clinical trial is ongoing and includes more than 30,000 people in the US. The early-stage, interim analysis included 95 participan­ts with confirmed cases of Covid-19, of which 90 had received the placebo and five the active vaccine.

The 95 cases included 15 older adults – aged 65 and over – as well as 20 people who were not white, including 12 from Hispanic or Latino/a background­s, four AfricanAme­ricans, three Asian-americans and one who was multiracia­l.

Severe cases of coronaviru­s were also examined, including 11 in the first interim analysis. All 11 cases occurred in the placebo group and none in the group which had received the vaccine, known currently as MRNA-1273.

Dr Stephen Hoge, president of Moderna, said he “grinned ear to ear” when learning about the potential efficacy of the vaccine.

He said: “When we got the news from the data and safety monitoring board. I’ll admit I broke character and grinned ear to ear for a minute. Because I didn’t expect, I don’t think any of us really hoped that the vaccine would be 94% effective at preventing Covid-19 disease, that was really a stunning realisatio­n.”

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