Daily Express

WONDER NHS DIET TO BEAT DIABETES

Scientists discover why sufferers get Type 2 disease

- By Giles Sheldrick Chief Reporter

RADICAL new action to reverse diabetes will see sufferers restricted to just 800 calories a day.

The liquid diet – available on the NHS for the first time – was shown to put Type 2 into remission.

It follows evidence that the lifestyle-driven disorder is triggered when excess fat spills from the liver into the pancreas.

Five thousand obese patients will be handed a daily soup and shake plan when the programme starts in April. The NHS

currently issues advice on how to eat more healthily and exercise.

If successful the diet could become a new treatment for that condition that currently costs the NHS £14billion a year.

Professor Roy Taylor, of Newcastle University, said: “This means we can now see Type 2 as a simple condition where the individual has accumulate­d more fat than they can cope with.

“Importantl­y, this means through diet and persistenc­e patients are able to lose the fat and potentiall­y reverse their diabetes.

“The sooner this is done after diagnosis, the more likely it is remission can be achieved.”

In tests overseen by the medicine and metabolism expert, one quarter of those on the 800-calorie liquid daily diet for 12 months lost 2st 5lb (15kg) or more and almost nine in 10 of this group put Type 2 into reverse.

Generally, the NHS recommende­d daily calorie intake is 2,000 calories a day for women and 2,500 for men.

Almost 4 million are blighted by the disease, with that number likely to rocket to 5.5 million by 2030. One in 10 over-40s already battle the condition that can lead to blindness, amputation­s, heart disease and kidney failure.

Another 12.5 million are at increased risk because of chronicall­y unhealthy lifestyles.

In studies carried out at Newcastle University’s Institute of Translatio­nal and Clinical Research, Prof Taylor and Prof Mike Lean, of Glasgow University, proved Type 2 was triggered when fat spills from the liver into the pancreas.

The discovery was made in studies on those who previously had the disease but lost weight and successful­ly reversed the condition as part of the pioneering Diabetes Remission Clinical Trial study.

The biggest research investment in history was funded with £2.8million from Diabetes UK.

More than a third were free of diabetes and off all medication for at least two years but a small group went on to regain weight and redevelope­d Type 2. Prof Taylor said: “We saw that when a person accumulate­s too much fat, which should be stored under the skin, then it has to go elsewhere in the body.

“The amount that can be stored under the skin varies from person to person.

“When fat cannot be safely stored under the skin, it is then stored inside the liver, and overspills to the rest of the body, including the pancreas.

“This clogs up the pancreas, switching off the genes which direct how insulin should effectivel­y be produced, and this causes Type 2.” The study confirms his socalled Twin Cycle Hypothesis – that

Type 2 is caused by excess fat gradually building up within both the liver and pancreas, but that the process is reversible.

Type 2 is much more aggressive in children and young people than adults, with a higher overall risk of complicati­ons appearing much earlier.The risk of developing the condition is significan­tly increased by being overweight or obese.

Symptoms include spending a penny more frequently, a greater thirst than normal, feeling more tired than usual and weight loss – all of which can be easily missed. By the time it is diagnosed one in three already have complicati­ons with their eyes, feet, kidneys or nerves, with some needing amputation­s.

Of major concern to health chiefs is that the proportion of young adults diagnosed with Type 2 has risen by a third since 2000. Around one in eight new cases is in someone aged between 18 and 40. A decade ago no child in Britain had Type 2, but there are now hundreds with the disease.

Nine in 10 sufferers are overweight or obese and do not produce enough insulin – the hormone regulating blood glucose – or the insulin they produce is insufficie­nt.

In Type 2, the pancreas becomes unable to produce insulin fast enough and the cells do not react to it properly, meaning glucose remains in the bloodstrea­m and is not used as fuel for energy.

The National Obesity Forum said: “Of the 5.5 million diagnoses projected for 2030, thousands will be children.That will be shocking.”

4 million people are blighted by the disease

‘Diet and persistenc­e can potentiall­y reverse their diabetes’

TYPE 2 Diabetes is one of the most overwhelmi­ng medical problems of our times. In the UK alone, four million people are blighted by it – an astonishin­g ratio of one in 10 people aged over 40.

So we should all be thankful that British scientists have brought sufferers a great Christmas gift, by demonstrat­ing that a managed 800-calorie-a-day diet can actually reverse the condition.

They proved it by bringing nine in 10 Type 2 sufferers into remission.

The results are considered so significan­t that next year, low-calorie liquid food will be given to NHS patients for the first time.

Simply put, Type 2 Diabetes is triggered when fat spills from the liver into the pancreas and the body cannot cope.

It can lead to blindness, amputation­s, heart disease and kidney failure.

The breakthrou­gh will be a boon for the NHS, which spends £14billion a year on Type 2 treatment alone.

And it will help future generation­s as the proportion of young adults diagnosed with Type 2 has risen by a third since 2000.This discovery will benefit us all.

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