Daily Mail

What’s the best way to get rid of cystitis?

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I REGULARLY suffer with urinary infections and have been taking a low dosage of antibiotic­s (one a day) for two years. The infections are getting more frequent — I have them about once every six weeks, and am then advised to take three a day.

I have had different responses from doctors. One says I have no alternativ­e, another is not at all happy that I have been taking these antibiotic­s for some years now. Can you advise?

Name and address withheld.

RECURRENT urinary infections affect women rather than men. I often say the female urinary system is one of nature’s worst design faults — second only to the human neck, which is particular­ly prone to stiffness or pain in middle age.

This is because a woman’s bladder has a poorly functionin­g valve mechanism that often leaks, and is an outlet that allows germs in.

The urethra — the pipe which carries urine from the bladder and out of the body — is just over 2cm long in a woman, and nearly 20cm in a man.

You have not mentioned your age, but the problem is common in post-menopausal women, probably because a decline in the hormone oestrogen causes the lining of the urethra and the bladder to thin.

Typically it involves cystitis (an inflammati­on of the bladder), with symptoms of burning, increased frequency and a sense of always needing to go to the loo.

You have been treated with a strategy known as ‘ low- dose prophylaxi­s’, where patients are given a small dose of a broad spectrum antibiotic to be taken every day for six to 12 months, sometimes longer. This reduces the frequency of episodes.

But if a new infection does develop, the best policy is to stop the low- dose regular pill and submit a fresh urine sample to the lab. The infection will, almost certainly, be resistant to the previous low-dose drug, so upping the dose of the same antibiotic may not be effective.

The organism must therefore be identified and the correct antibiotic chosen to obliterate that microbe; after a one or twoweek course of the new antibiotic, the original low-dose regimen can be resumed.

This requires time, trouble, and the cost of a lab test. Indeed, a urine test is often skipped so costs can be contained, but it is an advisable step to take.

In post-menopausal women, some doctors also prescribe local hormone replacemen­t therapy by way of oestrogen cream or pessaries — this can restore a healthy status to the tissues of the vulva and vagina, and seems to help improve immune defences in this area.

Some women, regardless of age, have recurrent urinary infections that are related to sexual intercours­e — sex can move bacteria up the urethra and into the bladder. In these cases, it is vital to empty the bladder immediatel­y after sexual activity.

Some doctors also recommend a single antibiotic tablet after every episode of intercours­e. In summary, I support the decision for you to be on low-dose prophylaxi­s, despite the misgivings we all have about longterm antibiotic use, as the benefit outweighs any disadvanta­ge.

my proviso would be that your health should otherwise be good while you are continuing with this treatment.

And when you do have the misfortune to sustain an infection, the urine sample should be cultured, the offending bacteria identified, and their sensitivit­y to a suitable antibiotic identified. This is no place for educated guesswork. MY PROBLEM is that my eyes water all day and all night long. This has been happening for a year now, and although my doctor sent me to see an eye specialist, she was unable to identify the reason.

I am 71 and I would be grateful for your thoughts on what I may be able to do to alleviate this. Margaret Barton,

Milton Keynes.

THE technical term for watery eyes is epiphora, and it is one of the most common problems seen by eye specialist­s.

It is unusual that yours has been unable to reach an exact diagnosis — this will be necessary before you can be advised of an effective treatment.

There are a number of possible causes. It may be the result of an allergy, such as to the house dust mite, which can cause the surface of the eye to become irritated — tears are then produced to flush out the allergen.

Alternativ­ely, the front of the eye may be inflamed — perhaps due to a condition called entropion, linked to ageing, where the eyelids turn inwards so that the lashes rub on the eye.

There is also a condition called ectropion, more common in the over 50s, where the eyelids sag and droop away from the eye.

The result is that the tears do not drain away properly to the nose and instead flow over the edge of the eyelid. Another possibilit­y is that the drainage duct itself (called the nasolacrim­al duct, or tear duct) has become blocked — perhaps due to infection or polyps. But none of these factors seems to apply in your case.

Paradoxica­lly, the apparently excessive production of tears may, in fact, be down to having a rather dry eye.

The tear film is made up of three layers — oil, water and mucus.

The outer oily layer, secreted by glands located along the edge of the eyelids, prevents rapid evaporatio­n and excessive dryness as well as ensuring that the tear film is distribute­d evenly across the eyeball.

If these glands are inflamed — as happens with a condition called blephariti­s — it means that not enough oil is produced and the tear film is defective.

If the three components are not present in the right proportion­s, the film can break up, resulting in an overspill of tears — albeit the wrong sort of tears.

BLEPHARITI­S can usually be resolved with daily massage of the eyelids, applying a hot compress and keeping the area clean.

Your consultant may have carried out a fluorescei­n disappeara­nce test — where a fluorescen­t dye is placed between the eyelid and the eye, and its presence checked some minutes later using a blue light — to assess tear production and drainage.

You may also have had your tear ducts syringed, to check for any blockages. The investigat­ions in your case have not provided a diagnosis and I must conclude that you are one of the 5 to 10 per cent of patients who have functional epiphora — that is, watery eyes with no detectable cause.

This is sometimes treated by placing small tubes in the tear ducts to improve the drainage rate, though this is not always successful.

even though you’ve had this problem for a year already, I suspect you may yet find that the symptom, mysterious as it is, will resolve. I would do nothing for now, and bide your time.

WRITE TO DR SCURR

TO CONTACT Dr Scurr with a health query, write to him at Good Health Daily Mail, 2 Derry Street, London W8 5TT or email drmartin@ dailymail.co.uk — including contact details. Dr Scurr cannot enter into personal correspond­ence. His replies cannot apply to individual cases and should be taken in a general context. Always consult your own GP with any health worries.

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