Daily Mail

Backlash by top scientists over designer baby technique

- By Victoria Allen Science Correspond­ent

SCIENTISTS have warned against allowing babies to be born with edited genes.

It comes after a world first technique was unveiled to ‘fix’ an embryo’s faulty DNA, which could eventually eradicate genetic diseases such as cystic fibrosis and breast cancer.

Amid debate the breakthrou­gh could pave the way for designer babies, internatio­nal experts put out a statement concluding it would be ‘inappropri­ate’ for a woman to become pregnant with a geneticall­y altered embryo.

They raise public concerns that editing an embryo to fix a genetic disease could be seen as ‘playing God’ in an effort to create only the ‘best children’ possible.

It could also damage the ‘unconditio­nal’ love parents have for their children by making them aware of genetic ‘imperfecti­ons’.

The statement, led by Stanford University in the US and endorsed by eight organisati­ons including the UK’s Wellcome Genome Campus, took 17 months to produce. It concludes: ‘At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropri­ate to perform germline gene editing that culminates in human pregnancy.’

The expert opinion follows controvers­y over the ethics of the first successful attempt, led by scientists from Oregon Health and Science University, to use gene editing to cut out DNA from a fertilised egg. This prevented a gene causing a deadly heart condition being passed on.

But the scientists’ statement, published in the American Journal of Human Genetics, discusses public fears of eugenics being used to create a superior race.

It warned: ‘The ability to “easily” request interventi­ons intended to reduce medical risks and costs could make parents less tolerant of perceived imperfecti­ons.

‘Perhaps the most deeply felt uneasiness is conceptual: the sense that in identifyin­g some individual­s and their traits as “unfit”, we experience a collective loss of our humanity. Often articulate­d as a concern is that we might be “oversteppi­ng” and “playing God”.’

This terrifying prospect: Page 18

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