Daily Mail

HRT therapy is a danger to Semenya say experts

- By MATT LAWTON Chief Sports Reporter

CASTER SEMENYA will return to the track this evening no doubt aware that she will be subjected to scrutiny that goes way beyond her ability as an outstandin­g 800metres runner with two Olympic and two world titles.

The debate as to whether the 26-year-old South African woman should be allowed to compete in a World Championsh­ip event will continue against the backdrop of Lord Coe and the IAAF — an organisati­on whose principal role should be to protect its athletes — trying to implement a rule forcing her to have Hormone Replacemen­t Therapy (HRT) if she wants to keep running as someone with hyperandro­genism.

But a Stanford University professor has not only exposed serious flaws in the scientific study being used by the governing body in the case they are submitting to the Court of Arbitratio­n for Sport (CAS), she has raised concerns about potential health risks to athletes like Semenya should they force her take medication.

Katrina Karkazis is a senior research scholar at Stanford University, and testified in the Dutee Chand case that persuaded the Court of Arbitratio­n for Sport to suspend the IAAF’s testostero­ne rule for two years in 2015. ‘Lowering testostero­ne can have serious lifelong health effects,’ she explained. ‘If done via surgery, women are at high risk for osteoporos­is.’

Karkazis is writing a book on testostero­ne and in an article she co-wrote with Gideon Meyerowitz -Katz, a chronic disease epidemiolo­gist in Australia, she challenged the validity of a study the IAAF commission­ed to submit as evidence to CAS. ‘The IAAF is heralding this study as major and important evidence. It isn’t,’ write Karkazis and Meyerowitz-Katz.

‘CAS has been clear about what evidence it requires in order to uphold the regulation. The IAAF must show that female athletes with higher total T (testostero­ne) have a performanc­e difference that approximat­es what male athletes typically have over female athletes; not that female athletes with higher T have a competitiv­e advantage over their peers. In other words, it has to be a big performanc­e difference, which CAS put in the 10-12 per cent range. What the study found is nothing near this.’

The study, widely quoted in the media after Semenya (above) denied Britain’s Laura Muir a medal in the 1500m, claims higher testostero­ne levels can give an 800m runner a 1.8 per cent advantage. ‘The IAAF has had six years to assemble evidence for this regulation,’ Karkazis and Meyerowitz-Katz write.

‘Currently, they have presented one opinion piece and these two studies. Even some who have supported the regulation agree these studies are not persuasive or pivotal.’

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