Daily Mail

Could eating chocolate make my reflux worse?

- Philip Dominey, Bristol.

I HAVE gastric reflux and have heard chocolate can make it worse, as it relaxes the lower sphincter in the oesophagus. Has this been proven? If so, I’d be willing to forgo my treats.

YOu pose a fascinatin­g question, but I must say, I have not been aware of a direct link between chocolate and acid reflux.

Gastric, or oesophagea­l, reflux describes the travelling of stomach contents back up into the oesophagus — a reversal of the normal flow.

this is due to a poorly functionin­g lower oesophagea­l sphincter, a ring of muscle at the top of the stomach that normally shuts to stop the contents of the stomach leaking out and up the foodpipe.

the contents are mixed with the hydrochlor­ic acid produced by the stomach lining to aid digestion, so they are highly acidic — but the lining of the oesophagus is not adapted to this.

As the acidic liquid moves up the oesophagus, the result is inflammati­on, which can be severe and may cause both cramp-like spasm and pain — classic symptoms of reflux.

repeated reflux over many years can damage the oesophagus lining — a condition known as Barrett’s oesophagus.

Multiple factors may upset the normal function of the sphincter — for example, a hiatus hernia (where part of the stomach squeezes up into the chest through an opening in the diaphragm), smoking and obesity, which can all reduce the tone of the muscles of the sphincter. CertAIn

foods, including peppermint, can irritate the muscle. But chocolate? Here, the evidence isn’t clear. Chocolate contains a mix of chemical components that not only give it its bitter taste, but have been known to affect the levels of various brain chemicals.

two chocolate chemicals, which are known central nervous system stimulants, are caffeine and theobromin­e. the cocoa bean contains about 0.2 per cent caffeine (by comparison, tea leaves are 3 per cent and coffee beans 1.2 per cent before they are brewed).

the theobromin­e content in cocoa beans is greater, at 1 per cent, and, as well as affecting the central nervous system, it is a heart stimulant. this increases the heartbeat and dilates blood vessels. Other molecules in chocolate that are active in the brain include salsolinol (which also occurs naturally in brain tissue), anandamide, a cannabisli­ke brain chemical that may have roles in feeding and sleep behaviours, and phenylethy­lamine, which could have moodenhanc­ing effects.

Clearly, chocolate is a moodalteri­ng food, but I find no evidence of any of these chemicals having a direct action on gut motility or, specifical­ly, the lower oesophagea­l sphincter.

Some anecdotal evidence suggests that caffeine and theobromin­e may worsen reflux symptoms by increasing acid production. But the scientific evidence has been inconclusi­ve, and the amount found in chocolate is low and makes this unlikely to be a significan­t trigger.

My view is that, if you wish, you should continue to enjoy chocolate — provided, of course, you do not experience a direct link between your symptoms and the act of eating chocolate or drinking cocoa, which would speak for itself.

AFTER a fall, I was diagnosed with severe osteoporos­is in my back and hip. My doctor recommends yearly infusions of a drug and vitamin D tablets. But I’m afraid that the sideeffect­s will make me feel worse,

particular­ly as I suffer with back spasms and am more or less housebound. Is it worth having treatment, given my condition is so advanced? I am 66.

Anne Luscombe, Plymouth. OSteOpOrOS­IS makes fractures more likely — even after minimal or no obvious trauma — as reduced bone mass means strength is lost. It seems the first sign of your condition came after you suffered a fracture following a bad fall. the experience must have been a shock.

Given your descriptio­n, I believe you had a fracture of the lower vertebrae in your spine — those being the bones that carry the greatest load and, as a result, are particular­ly prone to fractures.

However, the prospects for reducing your chances of further fractures — and, therefore, pain and disability — are good.

the preferred method of screening for osteoporos­is is DeXA scanning, a type of X-ray. results are presented as what is called a t-score, with osteoporos­is defined as a t-score below minus 2.5.

You mention in your longer letter that your t-score is minus 5.5 — this is significan­tly low, so treatment is essential to prevent further fractures.

I would suggest that you carry on with the regimen prescribed, unless instructed otherwise by a specialist. And rest assured, the side-effects should be minimal.

the intravenou­s treatment that has been proposed for you is zoledronic acid, a type of drug known as a bisphospho­nate that’s given once yearly as an injection into a vein over 15 minutes (known as an infusion).

Bisphospho­nates are used to prevent and treat osteoporos­is by inhibiting the process by which bone is broken down. they are very effective and well tolerated.

the potential side-effects may be flu-like symptoms for 24 to 72 hours after the first dose, but these can be eased with paracetamo­l. Subsequent doses should not cause this side- effect. In combinatio­n with calcium tablets and vitamin D (which helps the body absorb calcium), this will help reduce the risk of fractures. EXerCISe

can also help reduce fracture risk, by improving bone density (it helps to stimulate the action of osteoblast­s, which build bone cells) and by cutting falls due to improved balance and muscle strength.

Whether treatment now will help your back spasms is uncertain from the informatio­n you have given me. this may be due to other mechanisms, such as a compressed nerve in the spine, rather than a direct symptom of osteoporos­is. Your specialist will have a view about this and will investigat­e further if necessary.

there are other treatments you can discuss with your rheumatolo­gist. One is denosumab, an antibody that acts on factors involved in the formation of the cells that break down bone.

Another is parathyroi­d hormone, which involves a daily injection for two years, stimulatin­g bone formation. there is also calcitonin, a hormone that acts on calcium concentrat­ion in the body.

But, in my experience, the benefits of the once- yearly bisphospho­nate can be considerab­le and the side- effects are minimal. It is without doubt your best option, and not to be feared.

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 ??  ?? Every week Dr Martin Scurr, a top GP, answers your questions
Every week Dr Martin Scurr, a top GP, answers your questions

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