Daily Mail

Gene-edited wheat ‘with 85 per cent less gluten’

- By Colin Fernandez Science Correspond­ent

SCIENTISTS have used geneeditin­g techniques to all but eliminate gluten in wheat, potentiall­y making it safe for those with coeliac disease.

People with coeliac disease cannot eat gluten as the wheat protein can cause major damage to their digestive systems.

The disease affects around one in 100 people and causes a severe reaction to strains of gluten known as gliadins. If those afflicted eat gluten, it can cause complicati­ons including gut cancer in the long term.

But they may have been given a lifeline by researcher­s, who are on the brink of creating wheat that is gluten-free.

Scientists from the Institute for Sustainabl­e Agricultur­e in Cordoba, Spain, have created wheat that contains just 15 per cent of the gliadins found in normal wheat.

They used a tool that can ‘cut and paste’ sections of DNA called Crispr-Cas9 to remove genes for gliadins.

Out of a total of 45 genes that code for gliadins, the researcher­s, who published their results in the Plant Biotechnol­ogy Journal, managed to knock out 35.

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