Daily Mail

Found, 20 genes linked to being transgende­r

- By Colin Fernandez Science Correspond­ent

SCIENTISTS have uncovered 20 genes linked to being transgende­r – supporting claims that the condition has a physical basis.

Researcher­s believe the gene variations may contribute to people identifyin­g with the opposite sex.

Critics of transgende­r identity say the condition is ‘all in the mind’, and transgende­r people have a psychologi­cal problem rather than a medical one. But by highlighti­ng genetic mutations that affect brain developmen­t, the latest findings point towards transgende­r identity having a physical basis.

US researcher­s tested 14 female-to-male and 16 maleto-female patients at gender reassignme­nt clinics.

Presenting their research at the Society for Reproducti­ve Investigat­ion conference, the researcher­s said: ‘We identified genetic variants in 20 genes that may play a role in transgende­r identity.

‘The most promising of these include variants of genes involved in neurologic developmen­t and sex hormones.’

Dr Ricki Lewis, a geneticist, said: ‘These are highly reputable folks going about this exactly the right way, searching the genomes of transgende­r people to highlight which genes they have variants in. It lends legitimacy, if that needs to be added, that transgende­r is not a choice but a way of being.’

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