Daily Mail

WHY ANTIBIOTIC­S STOP WORKING

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ONE of the main causes of antibiotic resistance is overusing antibiotic­s and prescribin­g them inappropri­ately.

Bacteria become resistant to antibiotic­s because they pick up genetic changes, known as mutations, as they divide.

‘Most mutations kill or slow them down, but others provide a new characteri­stic and a way to survive, such as protecting the bacterial cell from the effects of an antibiotic,’ says microbiolo­gist Dr Adam Roberts. ‘Because they replicate so quickly, this means the bacteria that survive an antibiotic attack then produce more resistant bacteria — these can quickly take over, so the entire population is made up of resistant bugs.’

Continuall­y growing bacteria in the presence of antibiotic­s (which is effectivel­y what happens when the drugs are taken when they’re not useful or needed) encourages this process.

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