Daily Mail

How YOU have paid to help legalise lethal mind-bending party drugs

. . . because your taxes have been spent to test their use for depression — in a programme backed by an aristocrat­ic cheerleade­r for LSD

- By JONATHAN GORNALL

They were the mind-altering drugs of the Sixties, but now lysergic acid diethylami­de (better known as LSD), magic mushrooms and a range of other banned psychedeli­c drugs are making a comeback. Not on the party scene, but as the focus of researcher­s who believe they could treat a variety of mental health problems, including depression.

British researcher­s are at the forefront of this renaissanc­e of hallucinog­enics. But, as Good health can reveal, a key organisati­on funding their work is a pressure group with a parallel agenda.

In addition to supporting research into the potential therapeuti­c benefits of banned drugs, the Beckley Foundation — created by Amanda Feilding, a wealthy countess who’s spent a lifetime advocating the benefits of LSD — is working ‘to erode the pervasive taboo surroundin­g . . . recreation­al drug use’.

It would be wrong to dismiss the ‘ Cannabis Countess’ (who’s previously advocated legalising the drug) as simply a colourful character.

For here we reveal the extent of her influence in this controvers­ial area, both in funding the research and also actively participat­ing ‘ in the inception, design, and writing up’ of no fewer than 37 studies — despite the fact that she has no scientific qualificat­ions.

In 2012, there were just 58 papers exploring the effects and possible medical benefits of LSD, psilocybin ( the active ingredient in magic mushrooms) and ayahuasca, a mind-altering plant used in rituals by Amazon tribes. In the past year alone, there have been at least 135.

In the vanguard are researcher­s at Imperial College London. Known as the Psychedeli­c Research Group, they’re exploring the potential of banned drugs for treating conditions including depression and even for dealing with grief.

One of the key figures is David Nutt, the psychiatri­st and professor of neuropsych­opharmacol­ogy at Imperial who, in 2009, had to resign as the government’s chief drugs adviser after he said that LSD, ecstasy and cannabis were less harmful than alcohol. SINCe

then, Professor Nutt has collaborat­ed with the Beckley Foundation and its founder Feilding — the two are co-directors of what is described by the foundation as the Beckley Imperial Research Programme. Despite lacking scientific qualificat­ions, Feilding is co-author of 24 papers published by researcher­s at Imperial College London and is one of the 32-member team of the Psychedeli­c Research Group, as is Professor Nutt.

Feilding’s involvemen­t may raise a serious question about her foundation’s twin agendas.

On its website, it seeks donations to ‘support psychedeli­c research’, but also ‘drug policy reform’. Feilding herself insists that the war on drugs has failed and has campaigned tirelessly for reform.

In Jamaica, where Feilding has a house, the foundation played a role in the government’s decision to decriminal­ise cannabis.

At a conference in 2015, Feilding expressed the hope that ‘ the United Kingdom will learn some lessons from Jamaica’s progress, and will at least begin by recognisin­g the rights of those in need of access to cannabis for medicinal and religious purposes’.

But more disturbing, perhaps, is her support for ‘ microdosin­g’, where small amounts of psychedeli­cs are taken supposedly to achieve greater creativity; worryingly, some are reportedly using it to treat depression and anxiety.

At a psychedeli­cs conference in the U.S. last year, Feilding spoke of her use of LSD when younger to ‘hit that sweet spot, where vitality and creativity are enhanced’, a practice she compared to ‘ what people are now doing with microdosin­g’.

She added that microdosin­g ‘may indeed be the way we break down barriers, and make the psychedeli­c experience more accessible to people at large’.

Another member of the Beckley Imperial Research Programme with links to the countercul­tural aspects of psychedeli­c drugs is Dr Robin Carhart-harris, a frequent co-author on papers with Feilding.

In 2016, he addressed a London conference of The Psychedeli­c Society, which ‘ advocates the careful use of psychedeli­cs as a tool for personal and spiritual developmen­t’ (such drugs, it says, are banned solely ‘on the basis of unsubstant­iated health risks and tabloid hysteria’).

This isn’t the first time scientists have experiment­ed with mindalteri­ng drugs for mental health conditions. Between 1954 and 1965 psychiatri­sts at British hospitals used LSD to treat patients. This ended in 1966, when it was banned amid fears it caused delusions and suicidal thoughts. BUT

according to Professor Nutt, clinical use and studies before the ban showed that patients with disorders such as depression had ‘sometimes benefited considerab­ly’ from the ability of ‘the classical psychedeli­c drugs . . . to “loosen” otherwise fixed, maladaptiv­e patterns of cognition and behaviour, particular­ly when given in a supportive, therapeuti­c setting’.

he believes such drugs ‘may have a place in the treatment of neurotic disorders, particular­ly depressive disorder, anxiety disorders, addictions and in the psychologi­cal challenges associated with death’.

But for psychedeli­c treatment to become a reality, what’s needed are large- scale scientific trials. Now, thanks to the support of the Beckley Foundation, that’s about to happen.

Imperial’s Psychedeli­c Research Group has been recruiting patients with long-term depression for a major trial comparing the effects of a six- week course of the antidepres­sant escitalopr­am with a single dose of psilocybin. Dr Carhart-harris, Professor Nutt and Feilding are the leading members of the research team.

Imperial wouldn’t say if funding is forthcomin­g from the Beckley

Foundation for this study. But in a response to a Freedom of Informatio­n request we sent, it revealed that since 2009 it has received ‘a total of £108,519’ from the Foundation for ‘research projects’.

Public funding has also been provided for psychedeli­c research. In 2012, the Medical Research Council (MRC) gave Professor nutt £ 500,000 for research into psilocybin to treat major depression.

The next year they gave him £250,000 for a study on psilocybin and schizophre­nia. And the national Institute for Health Research, the research arm of the nHS, told us it funded ‘a small proportion’ of Professor nutt’s salary.

The new trial follows on from a series of studies by Professor nutt and colleagues at other UK institutio­ns since 2010 involving psilocybin for depression.

Some involved healthy volunteers. But then, in 2016, a team from Imperial, University College LLondon, Barts Health NHS Trust, King’s College and the Maudsley Hospital coconducte­d the first trial with patients. Involving just 12 ppeople, it was designed to investigat­e the safety and feasibilit­y of psilocybin for major longterm depression. As The Lancet Psychiatry reported, eight of the patients were ‘depression-free’ one week after treatment; five were still clear after three months. But all experience­d ‘ transient anxiety’ and nine also reported ‘transient confusion or thought disorder’.

Last December, Compass Pathways, a new UK company whose expert advisers include Dr Carhart-Harris and Professor Sir Alasdair Breckenrid­ge, former chair of the drug watchdog the Medicines and Healthcare products Regulatory Agency, announced a programme of clinical trials of psilocybin.

In the past few years, the Psychedeli­c Research Group has also looked at the potential use of drugs such as LSD.

But are yet more drugs, not least mind-altering psychedeli­c ones, really the solution for conditions such as depression?

In fact, the recommende­d treatment is psychologi­cal therapy. But as the British Medical Associatio­n found this year, thousands of patients with serious mental health problems were waiting up to two years for treatments such as cognitive behavioura­l therapy. Too often ‘ the only thing on offer to patients with depression is medication, which often has significan­t unwanted side- effects and does not help everyone’, says Anne Cooke, editor of the British Psychologi­cal Society report, Understand­ing Psychosis And Schizophre­nia.

As for the use of psychedeli­cs to treat mental health problems, Ms Cooke, a consultant clinical psychologi­st at Canterbury Christ Church University, adds: ‘My understand­ing is they could be used as an adjunct to psychologi­cal therapy, to try to help the person enter a frame of mind where they can make best use of the therapy.

‘But the same can sometimes be achieved by other means, such as relaxation methods. And, as we know, these drugs can also have adverse effects, so it’s important to exercise caution.’

Paul Kinderman, a professor of clinical psychology at the University of Liverpool and a member of the Council for evidenceba­sed Psychiatry, agrees drugs such as psilocybin ‘might help’ encourage ‘flexible thinking’.

He’s even advising a european research project looking at psilocybin for depression.

But he says it’s ‘important we’re very cautious with drugs such as psilocybin and LSD’ and says he’s ‘ pretty sceptical’ generally about drug treatments for mental health: ‘I really worry that a lot of people in the mental health system have been prescribed too large quantities of too many drugs for too long.’

Amanda Feilding declined to comment.

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