Daily Mail

Overweight? Blame your caveman gene

- By Colin Fernandez Science Correspond­ent

A GENE dating back to cavemen could be to blame for overweight people piling on the pounds, a study suggests.

Around half of people in modern societies have the gene, which also increases the risk of diabetes. The gene was common when our ancestors were hunting mammoths and sabre-toothed tigers – before the invention of farming,

When agricultur­e started another version of the gene which helps to keep blood sugar low became more common. This mutation allows us to eat starchy and sugary foods such as wheat and rice without putting on too much weight.

UK researcher­s analysed DNA from ancient humans as well as 2,504 people today and found that the split between the ‘caveman’ gene and the modern gene is around 50-50. But in DNA samples taken from the bones of people before farming was developed, the older variant is more common. Professor Frances Brodsky, head of bioscience­s at University College London, said: ‘We found that people differ in how efficientl­y their bodies can manage blood sugar levels, resulting from an evolutiona­ry process that seems to have been brought about by changing diets.’

The gene CLTCL1 produces a protein that ‘transports’ sugar out of the blood, taking it to be stored in fat and muscle cells.

Study author Dr Matteo Fumagalli said: ‘The older version of this genetic variant likely would have been helpful to our ancestors as it would have helped maintain

higher levels of blood sugar during periods of fasting and this would have helped us evolve our large brains,’

nEATING chicken is just as bad as beef for raising cholestero­l levels, researcher­s have warned. Red meat, which also includes lamb and pork, generally has more saturated fat than white.

But a new study by scientists in Oakland, California, shows both white and red meat have equally harmful effects on blood fats. It found that plant proteins are the healthiest for blood cholestero­l.

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