Daily Mail

Not tonight, dear, I’ve got a tickly cough

- By Xantha Leatham

mEN suffering from coronaviru­s are likely to lose their sex drive, a study suggests.

Scientists have discovered a Covid-19 infection could deplete testostero­ne levels, leading to a loss of libido.

The deteriorat­ion of the sex hormone could also explain why male patients have a poorer prognosis, as scientists found the severity of the virus increased as testostero­ne levels decreased.

The researcher­s say their findings could lead to the possibilit­y of using testostero­ne-based treatments to try to improve survival rates.

The Turkish team looked at 232 male coronaviru­s patients. They split them into three groups – asymptomat­ic patients, symptomati­c patients who were hospitalis­ed, and patients who were in intensive care.

Analysis revealed that as men’s testostero­ne levels decreased, the probabilit­y of them being in intensive care ‘significan­tly’ increased.

Patients who died had much lower testostero­ne levels than the patients who survived. And almost two-thirds of the asymptomat­ic patients reported a loss in libido.

Selahittin Cayan, the lead author of the study, which was published in the journal The Aging male, said: ‘The mean testostero­ne decreased as the severity of Covid-19 increased. The total testostero­ne level was significan­tly lower in the ICU group than in the asymptomat­ic group.

‘We found hypogonadi­sm – a condition in which the body doesn’t produce enough testostero­ne – in 51 per cent of the patients.’ It is hoped the findings could help explain why so many studies have found that the prognosis for men who have Covid19 is worse than for female patients.

Professor Cayan said: ‘Testostero­ne is associated with the immune system of respirator­y organs, and low levels of testostero­ne might increase the risk of respirator­y infections. It could be recommende­d that at the time of Covid-19 diagnosis, testostero­ne levels are also tested.

‘In men with low levels of sex hormones who test positive for Covid19, testostero­ne treatment could improve their prognosis. more research is needed.’

Even in the early days of the pandemic, it became clear that men are more likely to die than women.

Scientists say one explanatio­n could be that men are more likely to engage in ‘risky behaviour’ such as drinking and smoking, which lead to cardiovasc­ular disease that could increase the chances of someone dying from Covid-19.

Allan Pacey, a professor of andrology at the University of Sheffield, said: ‘I don’t think we should be surprised that the Covid infection affects testostero­ne.

‘The receptor that the virus uses to get into human cells is on the surface of the cells that make testostero­ne – though this is the first paper to confirm that testostero­ne is affected.’

He said the suggestion that testostero­ne therapy might be a benefit to men was a ‘premature’ assumption to make without proper trials.

‘What is interestin­g is the suggestion of a link between Covid and sexual function,’ he added. ‘If the virus does do this to testostero­ne levels, then there’s no surprise that sexual function will go down. It may well be that for some men this is something that will be the case for a long time.’

‘Testostero­ne levels were lower’

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