Daily Mail

Lung cancer drug boosts AstraZenec­a

- By Jessica Clark

ASTRAZENEC­A’s blockbuste­r lung cancer drug boosts survival rates among patients, the pharma giant said yesterday.

In a shot in the arm for the Ftse 100 group, a trial revealed that Imfinzi showed promise in treating highly aggressive small cell lung cancer. AstraZenec­a said the trial demonstrat­ed ‘statistica­lly significan­t and clinically meaningful improvemen­t’ in survival of patients.

It comes as a shareholde­r rebellion brews over plans to pay AstraZenec­a boss Pascal soriot, pictured, £18.9m this year. the French-born businessma­n scooped his biggest pay packet ever of £16.9m last year – the fifth year in a row he has earned more than £15m.

Investors have been urged to block the ‘ excessive’ pay deal at next week’s annual general meeting.

But soriot, 64, has been credited with turning the Londonlist­ed drug maker’s fortunes around – tripling the company’s share price since he took over in 2012.

Soriot also fought off a hostile takeover attempt from Us rival Pfizer in 2014 and refocused the business on areas such as oncology.

Cancer treatments including Imfinzi – which is already approved for non- small cell lung cancer – accounted for 40pc of AstraZenec­a sales last year. Developing blockbuste­r drugs is crucial for pharmaceut­ical firms as patents run out on older treatments. And AstraZenec­a has been on a buyout spree to shore up its pipeline.

Last month it bought cancer treatment specialist Fusion Pharmaceut­icals for £1.9bn.

Since December, it has bought rare disease focused firm Amolyt Pharma for £ 800m, cancer therapy company Gracell for £950m and vaccine developer Icosavax for £900m.

Dan Coatsworth, investment analyst at broker AJ Bell, said ‘pharma companies can never stand still’ as ‘the pipeline needs to be kept stocked up’. ‘AstraZenec­a has spent £2.8bn in the past four weeks alone on two companies to fill its ever-important pipeline of treatments that will drive earnings in the future,’ he said. Imfinzi is already approved to treat non-small cell lung cancer. AstraZenec­a’s executive vice president of oncology research and developmen­t susan galbraith said the trial results were ‘exciting’. sheena Berry at investment manager Quilter Cheviot said the results were a ‘testament to the company’s strategic focus on oncology’.

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