Daily Mail

Doctors issue birth defects alert over ‘Ozempic babies’

- By Kate Pickles Health Editor

WEIGHT-loss jabs could cause birth defects if used by women hoping to become pregnant, doctors have warned.

A spate of women reported unexpected­ly getting pregnant after being prescribed medication­s containing semaglutid­e, the key ingredient in drugs Wegovy and ozempic.

This has led to some doctors in the Us prescribin­g the jabs to treat polycystic ovary syndrome ( PCos), one of the leading causes of infertilit­y in women.

But British scientists have warned the medication­s could cause abnormalit­ies and advised those taking it to use contracept­ive tion and stop taking it at least two months before trying to conceive. The jabs work by mimicking a hormone called GlP-1, which suppresses appetites and helps people to feel full faster.

Experts believe the ‘ozempic’ or ‘oops’ baby phenomenon could be down to a number of factors, with weight loss known to boost fertility by helping to regulate ovulation and menstruati­on. The drug may also increase the chance of pregnancy because side effects such as nausea and vomiting may stop con trace pre search er pills being absorbed effectivel­y. Experts cautioned against using the jabs to try to boost fertility after trials on animals found it was potentiall­y harmful.

specialist Professor Tricia Tan at Imperial College london said: ‘Women need to know that these drugs should not be used during pregnancy.

‘Animal studies did show that the animal babies born to animals who were given these medication­s had problems.’

Nerys Astbury, a senior

‘Shouldn’t be used in pregnancy’

in diet and obesity at oxford University, said nonpharmac­eutical routes to lose weight would be advised before pregnancy.

she said: ‘It is important to note that while some doctors are prescribin­g semaglutid­e off- label to women with PCos, it is not clear whether it’s safe to use in women during pregnancy and should not be used as a method to treat infertilit­y until research demonstrat­ing safety and effectiven­ess is available.’

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