Daily Mirror (Northern Ireland)

What next with Covid? The crucial questions answered

- BY MATT ROPER Matt.roper@mirror.co.uk @mattroperb­r

ANXIETY over coronaviru­s is rising along with the infection rate.

Here, Dr Mike Tildesley, an expert in mathematic­al modelling of infectious di sease, and P rof Martin Mckee, professor of European Public Health at the London School of Hygiene & Tropical Medicine, answer the key questions…

Q What’s really causing numbers to go up? Why are things worse in the North of England?

A The rising number of Covid cases is being driven by many different factors, according to Prof Mckee.

He says: “Many depend on circumstan­ces in each place.

“In some places, spread is mainly within households, but this is especially so when there are large numbers of people living i n multigener­ational homes. This is much less of a problem in, for example, Scandinavi­a.

“Clearly, universiti­es are now becoming a focus for transmissi­on in some places. “So are hospitalit­y venues.” He believes some parts of England, particular­ly in the North East and North West, were too quick to reopen.

He says: “It does appear that the decision was made on the basis of national figures rather than looking at the regional difference­s.”

Q Is it true spreading is done by a small number of super spreaders?

A Yes, says Dr Tildesley. He adds: “Work done in India recently suggested that a very small percentage of the population is causing quite a lot more of the infections.

“It may be that those people are more infectious and more likely to pass infection on, but probably more that their job or circumstan­ces bring them into contact with a greater number of people.”

Prof Mckee adds: “A lot of the spread is at super spreading events, as illustrate­d perfectly last week in the Rose Garden of the White House.

“That’s why we need a really good system of backwards contact tracing.”

Q Is it really pubs and restaurant­s that are to blame?

A Dr Tildesley says: “I think it’s unfair to put all the blame on to pubs or restaurant­s, but it’s clear that in settings where mixing is high the risk is greater.

“Currently under the Rule of Six you could meet five people for breakfast, five for lunch, five for dinner and five for drinks, and they could all be different.

“So a balance of risk, going to a pub or restaurant, is a high-risk activity when compared with other settings.”

Q Why don’t the local lockdowns seem to be working?

A Dr Tildesley points out that the much more severe national lockdown “reduced the R number to below one, but only just”.

He goes on: “Local lockdowns have been having some effect but they aren’t taking the R number below one.”

Prof Mckee blames the failure of the Government’s test-and-trace system, adding: “We have invested far too little in support for those who are isolating.”

Q If numbers keep going up after new restrictio­ns are brought in on Monday, what might be the next step?

A Another shorter national lockdown might be considered, especially if the NHS starts to become overwhelme­d,

believes Dr Tildesley. He says: “It might be a measure we have to take, but it’s a really difficult balancing act because of the effects on the economy and people’s wellbeing. It’s not an exit strategy or a solution but a short, sharp shock which might buy us some more time.”

Q Do we know more about how most people get infected? Do you have to spend a long time close to someone?

A Prof Mckee says: “Yes, we know a lot more about the virus. In particular, we know that it is mostly spread through airborne transmissi­on – aerosols that remain infectious when suspended in the air.

“While the initial advice about hand washing i s still valid , it points to the much greater danger from being indoors in settings where there are large numbers of other people.

“This is why we need to think very seriously about whether bars and restaurant­s should remain open at this time.”

Q

Some people are now saying that you don’t catch coronaviru­s from surfaces. How come?

A

Prof Mckee says: “It is still entirely possible to catch the disease from contaminat­ed surfaces.

“It’s just that this is now seen as relatively less important compared with airborne spread, because there are more cases of airborne infection.”

A

Prof Mckee says: “It does seem that people who are infected with a larger dose of the virus are more likely to get severe disease. However, there are many other factors involved, ranging from their genetic compositio­n to their underlying health conditions.”

Q What is the virus load? What effect does it have? Q What’s the truth ruth about the number of people who are asymptomat­ic?

A

Dr Tildesley y says: “This is one of the big unknowns.

Q What’s all the panic about if a vaccine for Covid is to start being rolled out next month?

UK are closed down for Christmas?

Dr Tildesley says: “I don’t believe that students should be kept on It’s because there is still huge campus, but I think we need to do what uncertaint­y about how effective a we can to make sure that the students vaccine will be and when one might be can go home safely. available, explains Dr Tildesley. “We might need to consider an isola

A

“Firstly, a vaccine will probably only be tion period for students before they leave Prof Mckee says there is no evidence available in relatively small numbers, and uni or after they arrive home, before they herd immunity could be achieved. it would take a really long time to ramp see vulnerable or elderly family members, He adds: “In theory, if about 60% of it up. Will it give everyone full immunity? so we can try to minimise that risk.” the population were infected we might “Will it prevent infection or stop people expect a degree of herd immunity. getting symptoms if they do get infected? “This is happening almost nowhere in “Will it be effective for the elderly? the world, and even where it is, like in the There are a lot of uncertaint­ies.” Amazon, there is evidence that the

A

Prof Mckee says: “It is certainly true immunity from infections, as opposed to that we can be reinfected. vaccinatio­n, may be quite short-lived.” Dr Tildesley says: “There have been “There is evidence immunity acquired i isolated cases detected in schools, by infection may not be so long-lasting.”

A

but often onl only one per school Dr Tildesley says the evidence suggests Dr Tildesley says: “The best case and those thos children or the disease might be less severe the scenario of course is we have a adults probably p got it second time around. vaccine that’s available in the very near somew somewhere else. The future that we can mass-produce. risk i in schools is “The worst case scenario is we could

A

extrem extremely low.” Dr Tildesley says: “We’re a little have to deal with some level of restric

Wh What is likely to behind other countries, but the UK tions for the foreseeabl­e future.”

hap happen when all is somewhat mirroring the situation in

the un universiti­es in the France and Spain. Germany interestin­gly

AQ What has been the experience with schools?

AAQ Is it true we can be reinfected with Covid and get it worse a second time? And does that mean a vaccine would be ineffectiv­e? Q How does the UK’S second wave compare to other countries now?

is not seeing the same kind of rise. Of course, our testing capacity is much better this time around, which muddies the waters in terms of comparing.”

Q Some are suggesting letting Covid spread among young, healthy people. Could herd immunity work? Q What are the best and worst-case scenarios for next year?

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Could herd immunity work?
 ??  ?? IN THE KNOW Dr Tildesley, left, and Professor Mckee
IN THE KNOW Dr Tildesley, left, and Professor Mckee

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