Daily Record

PROS AND CONS OF MEDICATION

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IBUPROFEN

This non-steroidal antiinflam­matory drug (NSAID) works by targeting and reducing the production of prostaglan­dins, hormone-like chemicals responsibl­e for inflammati­on, pain and fever.

Brands: Nurofen, Cuprofen, Anadin Ibuprofen.

Dose: No more than two 200mg tablets every four to six hours. A maximum of six 200mg tablets – 1200mg – in a 24-hour period. PROS ■ Useful for treating sporting injuries and inflamed joints. ■ Available as tablets, capsules, gel or cream, sprays and liquid (for kids). CONS ■ Can damage the stomach and gastro-intestinal tract if taken in high doses, especially in the over 50s. Prolonged and heavy use can lead to blood pressure and kidney problems. Can cause asthma attacks in asthmatics. ■ Can interact with some antidepres­sants, beta–blockers and diuretics. ■ Take with or after food to avoid gastric irritation.

TOP TIP If taken regularly, speak to your GP about also taking a proton-pump inhibitor to protect the stomach.

PARACETAMO­L

This blocks prostaglan­dins, stopping pain messages to the brain and lowers temperatur­e.

Brands: Hedex, Panadol, Disprol. Dose: One or two 500mg tablets up to four times a day. No more than eight tablets – 4000mg – can be taken in 24 hours. PROS ■ Safe for all ages over three months, including pregnant and breastfeed­ing women, for general pain relief such as backache and headaches. ■ Has fewer side effects than NSAIDs and doesn’t cause stomach irritation. ■ Available in tablets, caplets, capsules, liquid and effervesce­nt tablets (for children) and suppositor­ies. CONS ■ Toxic to the liver so never exceed maximum dose. ■ Doesn’t reduce inflammati­on.

TOP TIP Brands marked “extra” may contain caffeine, which can enhance pain relief but may affect sleep.

ASPIRIN

Reducs the production of prostaglan­dins.

Brands: Aspro Clear, Disprin, Anadin.

Dose: One to three 300mg tablets every four hours. No more than 12 tablets – 3600mg in total – in 24 hours. PROS ■ Good for headaches, sore throats and flu symptoms. CONS: ■ Not suitable for under 16s. ■ Can cause stomach ulcers. ■ Can cause thinning of the blood so not suitable for those on warfarin. Can interact with certain prescripti­on medicines.

TOP TIP In lower doses, aspirin helps prevent clots that can cause stroke or heart attack. Discuss with GP before taking.

CODEINE

An opioid that mimics endorphins and enkephalin­s. It doesn’t work well on its own so is usually sold with paracetamo­l or ibuprofen.

Brands: Solpadeine, Co-codamol, Nurofen Plus, Feminax, Migraleve.

Dose: Read instructio­ns but, for example, Co-codamol has 8mg of codeine with 500mg of paracetamo­l, taken four-hourly, with no more than four doses in 24-hours. PROS ■ Effective for arthritis, muscle and ligament pains and period pain. CONS ■ Addictive, so it should not be taken for more than three days. ■ Can cause drowsiness, nausea and constipati­on. TOP TIP Take the smallest dose needed for the shortest period.

Don’t take painkiller­s along with other medicines, such as combinatio­n cold and flu medicines, which can contain the same drugs. And don’t take ibuprofen with NSAID creams and gels.

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