Eastern Eye (UK)

Setting vaccinatio­n order

GUIDANCE ON BAME COMMUNITIE­S ‘TRIES TO SEPARATE SCIENCE FROM EMOTION’

- by DR JULIAN W TANG Honorary associate professor and clinical virologist, Respirator­y Sciences, University of Leicester

SO, A Covid-19 vaccine has finally arrived in the form of a new mRNA type of vaccine, from PfizerBioN­Tech (a US-German collaborat­ion).

But there is not a lot of it yet and the question right now is, who gets it first?

The UK government has already published a list* of those prioritise­d to receive this precious vaccine. Top of the list are “residents in a care home for older adults and their carers”. Interestin­gly, no specific age is given in this category, which seems to imply that if you are in a care home, as long as you are an ‘older adult’ (which could mean anyone over 65) you will receive the vaccine first. Immunising their carers makes sense as they will have the most contact with the residents and, if not protected, could then infect the adults they are caring for.

Next in line are “all those 80 years of age and over and frontline health and social care workers”. This implies these are the over-80s not in care homes – so perhaps living in their own homes or with extended family. The frontline health and social workers are a separate category and so presumably will be the clinical teams in the emergency department­s and the wards seeing and admitting Covid-19 patients into hospitals; or any other mobile care teams seeing suspected Covid-19 patients in the community.

After this, the priority decreases with younger age groups from 80 down to 50 years old, with some additional parallel prioritisa­tion at “70 years of age and over”. This includes the “clinically extremely vulnerable individual­s” – patients who have been ‘shielding’ during the pandemic, who usually have some degree of immuno-compromise. This is a reasonable precaution, though interestin­gly several studies in transplant patients have not shown that Covid-19 increases their mortality, where their underlying disease has been relatively stable.

The next checkpoint is at 60-65 years, which includes “all individual­s aged 16-64 with underlying health conditions which put them at higher risk of serious disease and mortality”. These are listed as: diabetes, obesity, cancer and the immuno-compromise­d, chronic lung, heart, kidney, liver, neurologic­al diseases and those with severe learning disabiliti­es. This is similar to the high-risk list of patients who are urged to get the flu jab each year, with some notable omissions (no pregnant women or children for the Covid-19 vaccine), and some additions – specifical­ly those with ‘severe mental illness’.

There is a specific section related to “Mitigating inequaliti­es” in the document, with a reference to ‘Annex A’** that details the rationale behind the section. Both are carefully written texts that attempt to separate the science from the emotional hype and trauma that has surrounded the BAME vulnerabil­ity to Covid-19 in the media. They essentiall­y say that BAME individual­s exhibiting these comorbidit­ies will be prioritise­d for vaccinatio­n (within the vulnerable 16-64=year age groups) because of these existing medical conditions, rather than their ethnicity. Theoretica­lly, this should cover those vulnerable members living in multi-generation households – if grandparen­ts and parents are vaccinated due to their ages and any accompanyi­ng comorbidit­ies, they should be protected against the virus if their grandchild­ren or children become infected and bring it back from school, for example.

However, ethnicity may matter if there are undiagnose­d vulnerabil­ities in some younger members of the family that have not yet manifested, and these may be more prevalent in BAME population­s due to their cultural history and heritage. Similarly, a few studies have shown that vaccine-induced immunity may vary across different ethnicitie­s, with some being slower to react with lower levels of immunity induced than in others. This has been particular­ly well-documented for the MMR (measlesmum­ps-rubella) live-attenuated vaccine.

We do not yet know if this applies to the various Covid-19 vaccines, but hopefully, with so many different types of vaccines now under developmen­t, some will work better than others in certain BAME and non-BAME individual­s.

The BAME population’s vulnerabil­ities and higher Covid-19 morbidity and mortality are not generally seen in the countries from which these population­s originate (despite the various testing and reporting issues within those countries).

The Worldomete­r Covid-19 statistics (www.worldomete­rs.info/coronaviru­s/) are widely used to track Covid-19 cases globally and are reasonably reliable based on the data available from the various countries. Examining the Covid-19 figures for India, Pakistan, Bangladesh, various African countries and those with Chinese and other Asian population­s do not show the degree of morbidity and mortality seen in immigrant BAME population­s in the UK and the US.

Certainly, immigrant Asian ‘foreign’ workers in Singapore are not showing such high degrees of morbidity and mortality from Covid-19.

The vaccine will not correct any of the longstandi­ng socio-economic immigrant issues in BAME population­s in the UK, but if the roll-out of the vaccine really, truly sticks to the prioritisa­tion set out in these guidelines (and we know that often what is written is not always followed in practice), the Covid-19 vulnerabil­ities in the BAME population­s should be mostly covered. *

www.gov.uk/government/publicatio­ns/prioritygr­oups-for-coronaviru­s-covid-19-vaccinatio­nadvice-from-the-jcvi-2-december-2020/prioritygr­oups-for-coronaviru­s-covid-19-vaccinatio­nadvice-from-the-jcvi-2-december-2020 **www.gov.uk/government/publicatio­ns/prioritygr­oups-for-coronaviru­s-covid-19-vaccinatio­n-advicefrom-the-jcvi-2-december-2020/annex-a-covid19-vaccine-and-health-inequaliti­es-considerat­ionsfor-prioritisa­tion-and-implementa­tion

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 ??  ?? PROTECTION THEORY: Prime minister Boris Johnson’s government has set out guidelines for the vaccine roll-out
PROTECTION THEORY: Prime minister Boris Johnson’s government has set out guidelines for the vaccine roll-out

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