BBC Science Focus

NEW TREATMENT RECHARGES DECISION-MAKING IN ALZHEIMER’S

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More effective treatments for Alzheimer’s disease could be just around the corner, thanks to a technique called deep-brain stimulatio­n (DBS), research just published in the Journal of

Alzheimer’s Disease suggests. Deep-brain stimulatio­n involves implanting electrodes inside a patient’s brain that stimulate key areas of the frontal lobe by means of a tiny electric current, provided by a ‘battery pack’ implanted in the patient’s chest. The technique has already proved successful in treating neurologic­al conditions such as depression and Parkinson’s disease, while in 2016, studies found that it could help to stimulate brain cell growth and slow memory loss.

Building on this research, a team at the Ohio State University led by Dr Douglas Scharre, gave three Alzheimer’s patients DBS implants then tracked their cognitive function over three years. All three patients experience­d less cognitive decline than would normally be expected, and in some cases there were actually signs of a reversal: one patient was able to cook a meal for the first time in several years.

“We have many memory aids, tools and pharmaceut­ical treatments to help Alzheimer’s patients with memory, but we don’t have anything to help with improving their judgments, making good decisions, or increasing their ability to [focus] on the task at hand. These skills are necessary in performing daily tasks,” says Scharre.

A follow-up study involving a much larger group of patients is now being prepared.

 ??  ?? The implanted electrodes trigger areas in the brain responsibl­e for decision- making and concentrat­ion
The implanted electrodes trigger areas in the brain responsibl­e for decision- making and concentrat­ion

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