Nottingham Post

US neurologis­t shares six ways he has slowed his Alzheimer’s

HIS EARLY DIAGNOSIS GAVE DR DANIEL GIBBS AN OPPORTUNIT­Y TO TRY AND IMPEDE ITS PROGRESS. ASKS HOW HE WENT ABOUT IT

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FOR most people, an Alzheimer’s diagnosis would be devastatin­g. But Dr Daniel Gibbs is not most people – he’s a neurologis­t who not only has specialist understand­ing of the condition, but also happens to have early-stage Alzheimer’s himself.

While he admits he’s “disappoint­ed” to have the disease, Dr Gibbs says he’s also “fascinated” by it - and considers himself lucky.

He stumbled upon his diagnosis 10 years ago, before he developed any cognitive symptoms (Dr Gibbs took a DNA test to trace his ancestry, which revealed genetic links to Alzheimer’s). This ultimately gave him the chance to tackle it very early on.

“It’s easy to say I’m unlucky to have Alzheimer’s,” says Dr Gibbs. “But in truth, I’m lucky to have found what I found, when I found it.”

As a result, the American neurologis­t, now 69, has devoted his time to researchin­g the disease and what can be done to slow its progress.

He’s now explained his findings in a new book – A Tattoo On My Brain: A Neurologis­t’s Personal Battle Against Alzheimer’s Disease – which reveals the lifestyle choices Dr Gibbs, and many in the dementia community, believe can help slow the progress of Alzheimer’s, particular­ly in its early stages. And by early, he means before there are even any symptoms (there can be changes in a brain with Alzheimer’s up to 20 years before there are any cognitive signs, Dr Gibbs points out).

He says he’s “still doing well” but started getting cognitive symptoms around nine years ago, when he began having problems rememberin­g the names of colleagues, and retired soon after. He now has increasing problems with his short-term memory, often can’t recall what he did an hour ago, and needs to write down all his plans and keep a meticulous calendar. Still, he insists: “Most people would have no idea I have Alzheimer’s.”

Dr Gibbs believes the lifestyle modificati­ons he’s made since his diagnosis have helped slow the progressio­n of the disease, and says such lifestyle measures also appear to reduce the risk of getting Alzheimer’s in the first place. “The important message is all of these modificati­ons are likely to be most effective when started early, before there’s been any cognitive impairment,” he says. “The pathologic­al changes in the brain that result in Alzheimer’s disease begin years before the onset of cognitive impairment – up to 20 years for the amyloid plaques. Once nerve cells in the brain start to die off and cognitive impairment begins, lifestyle modificati­ons seem to have less, if any, impact.”

Dr Gibbs says the same is probably true for drugs, adding: “The time to

Eat a plant-based diet intervene, both with lifestyle modificati­ons and with potential drugs, is almost certainly early, before significan­t cognitive impairment has occurred.”

Although the Alzheimer’s Society (alzheimers.org.uk) hasn’t seen Dr Gibbs’ book, Dr Tim Beanland, the society’s head of knowledge, agrees healthy lifestyle measures are thought to help slow the disease’s progress.

“There’s growing evidence to suggest regular exercise, looking after your health, and keeping mentally and socially active can help reduce the progressio­n of dementia symptoms,” says Dr Beanland.

“We know that what’s good for the heart is good for the brain, so a healthy diet and lifestyle, including not smoking or drinking too much alcohol, can help lower your risk of dementia, and other conditions like heart disease, stroke, diabetes and some cancers.”

Here, Dr Gibbs outlines six steps he says people can take to help reduce the risk and slow the progress of Alzheimer’s in its very early stages...

There’s overwhelmi­ng evidence that regular aerobic exercise reduces the risk of Alzheimer’s and slows the progressio­n of the disease in the early stages by as much as 50%, Dr Gibbs says. The evidence for a beneficial effect of exercise is robust except in the later stages of the

Keep your brain stimulated disease, when it may be too late to intervene effectivel­y.

1.Take regular exercise

2.Eat a plant-based diet

A plant-based, Mediterran­ean-style diet appears to reduce the risk of getting Alzheimer’s. The evidence is most compelling for a variant of the Mediterran­ean diet called the MIND diet (Mediterran­ean interventi­on for neurodegen­erative delay) that emphasises adding green vegetables, berries, nuts and other foods rich in flavanols.

3.Mentally stimulatin­g activity

While games and puzzles may be helpful, it’s particular­ly important to challenge the brain with new learning, as this is thought to help develop new neuronal pathways and synapses.

Examples include reading, learning to play a new musical piece, or studying a new language.

4.Social engagement

5.Getting adequate sleep

6.Diabetes and high blood pressure treatment

This can be hard for people living with Alzheimer’s because apathy is often a part of the disease. There’s evidence that those who remain socially active have slower progressio­n.

This is an emerging area of research. There appears to be a cleansing of the brain of toxins, including betaamyloi­d (a protein which forms sticky plaques in the brains of people with Alzheimer’s) during sleep by the so-called glymphatic circulatio­n. Also, sleep disorders including sleep apnoea are common in patients with Alzheimer’s and should be treated if present.

Both these disorders – diabetes and high blood pressure – can aggravate Alzheimer’s pathology in the brain as well as lead to vascular dementia, a condition that often coexists with Alzheimer’s.

Therefore, detecting these issues early and ensuring they’re well managed is also important.

■ A Tattoo On My Brain: A Neurologis­t’s Personal Battle Against Alzheimer’s Disease by Daniel Gibbs with Teresa H. Barker is published by Cambridge University Press, priced £18.99

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Dr Daniel Gibbs
Dr Daniel Gibbs was diagnosed with Alzheimer’s a decade ago Dr Daniel Gibbs
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Dr Tim Beanland
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