Runcorn & Widnes Weekly News

Test method is animal-free gamechange­r

- BY OLIVER CLAY

ASCI-TECH Daresbury biotech firm has declared a breakthrou­gh in the field of animal-free testing.

XCellR8 said its trademarke­d Ocular Irritectio­n uses a synthetic substitute to model the effects of chemicals on corneas – the clear outer part of the eye.

This provides an alternativ­e to other testing methods such as bovine corneas or other animal matter obtained from a slaughterh­ouse.

Results can be returned in four weeks with a final Good Laboratory Practice-regulated report in six to eight weeks.

A Sci-Tech Daresbury spokesman said XCellR8 has been based at the science campus since 2013 and is devoted to animal-free safety and tests for the cosmetics, personal care and chemical industries.

He said the Irritectio­n breakthrou­gh was developed by InVitro Internatio­nal and XCellR8 is the first company in the UK to offer this method.

The Irritectio­n technology was developed by InVitro Internatio­nal and XCELLR8 is the first company in the UK to offer this method (Ocular Irritectio­n OECD 496).

Dr Carol Treasure, co-founder and chief executive of XCellR8, said: “The announceme­nt of our new Ocular Irritectio­n test is a major breakthrou­gh for all of us who want to see a world without animal testing.

“Over recent years, the growing availabili­ty of in vitro testing services has been pivotal in preserving the lives of countless animals while simultaneo­usly improving the accuracy and reliabilit­y of tests that humans rely on to be sure that products are safe.

“However, the ongoing use of animal components in most of these tests compromise­s their human relevance and can affect the reproducib­ility of results – a factor that has not been generally considered until relatively recently.

“That coupled with the increasing consumer demand for vegan goods means that our Ocular Irritectio­n test is therefore a real game changer.

“This is a test completely free of animal products that does not compromise on quality or safety - what this means for a range of industries from personal care to chemicals is hugely exciting.”

John Downes, chief executive officer of Langtree and chairman of Sci-Tech Daresbury, said: “It’s testament to the expertise and dynamism of XCellR8 and the culture of innovation we’ve created on campus that such a landmark moment in animal safety has been created at Sci-Tech Daresbury.

“The Ocular Irritectio­n(R) test is hugely important breakthrou­gh at a time when how we treat the world around us, and our fellow inhabitant­s, has never been more important.

“It’s therefore a privilege for the campus to support XCellR8 on this latest stage of its very exciting journey.”

 ?? ?? ● XCellR8’s lab team, based at Sci-Tech Daresbury in Halton
● XCellR8’s lab team, based at Sci-Tech Daresbury in Halton
 ?? ?? ● Techspace One, a state-of-the-art business facility where XCellR8 is based
● Techspace One, a state-of-the-art business facility where XCellR8 is based
 ?? ?? ● Dr Carol Treasure, co-founder and chief executive of XCellR8, based at Sci-Tech Daresbury.
● Dr Carol Treasure, co-founder and chief executive of XCellR8, based at Sci-Tech Daresbury.

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