Jet lag pills can­cer hope

Scottish Daily Mail - - TERROR ON THE TUBE - By Lucinda Cameron

A DRUG used to ease jet lag could al­le­vi­ate the ‘dev­as­tat­ing’ im­pact of painful side ef­fects from can­cer medicines, Scots re­searchers have found.

Sci­en­tists be­lieve a drug known as mela­tonin can pre­vent pain caused when chemo­ther­apy dam­ages nerves.

Ex­perts say the find­ings could help sci­en­tists un­der­stand more about ways to limit painful side ef­fects of chemo­ther­apy.

Re­searchers from Ed­in­burgh and Aberdeen uni­ver­si­ties fo­cused on a con­di­tion known as chemo­ther­apy-in­duced neu­ro­pathic pain (CINP), which af­fects al­most 70 per cent of pa­tients.

The con­di­tion causes tin­gling and pain sen­sa­tion to touch and to cold tem­per­a­tures that can be se­vere enough to cause pa­tients to limit chemo­ther­apy.

A study with rats found mela­tonin could limit the dam­age to nerve cells if given be­fore chemo­ther­apy. But it did not al­le­vi­ate pain when CINP had de­vel­oped.

Ed­in­burgh Univer­sity’s Dr Carole Torsney, who co-led the study, said: ‘CINP can have a dev­as­tat­ing im­pact on pa­tients, and may limit chemo­ther­apy doses, with po­ten­tially se­ri­ous con­se­quences.

‘These find­ings are very ex­cit­ing and sug­gest that mela­tonin could pre­vent CINP.’

Newspapers in English

Newspapers from UK

© PressReader. All rights reserved.