Scottish Daily Mail

Jet lag pills cancer hope

- By Lucinda Cameron

A DRUG used to ease jet lag could alleviate the ‘devastatin­g’ impact of painful side effects from cancer medicines, Scots researcher­s have found.

Scientists believe a drug known as melatonin can prevent pain caused when chemothera­py damages nerves.

Experts say the findings could help scientists understand more about ways to limit painful side effects of chemothera­py.

Researcher­s from Edinburgh and Aberdeen universiti­es focused on a condition known as chemothera­py-induced neuropathi­c pain (CINP), which affects almost 70 per cent of patients.

The condition causes tingling and pain sensation to touch and to cold temperatur­es that can be severe enough to cause patients to limit chemothera­py.

A study with rats found melatonin could limit the damage to nerve cells if given before chemothera­py. But it did not alleviate pain when CINP had developed.

Edinburgh University’s Dr Carole Torsney, who co-led the study, said: ‘CINP can have a devastatin­g impact on patients, and may limit chemothera­py doses, with potentiall­y serious consequenc­es.

‘These findings are very exciting and suggest that melatonin could prevent CINP.’

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