Sunderland Echo

Anti-virus oral drug trial in North East

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Family doctors and health profession­als are enrolling people in the North East in a clinical trial investigat­ing the effectiven­ess of new oral treatments for COVID-19 which can be taken at home.

The Platform Adaptive trial of NOvel antiviRals for eArly treatMent of covid-19 In the Community (PANORAMIC) aims to assess a range of purpose-designed antiviral treatments which could help clinically vulnerable people with Covid-19 recover sooner and prevent hospital admissions.

Local people who receive a positive PCR test for Covid-19 will be contacted by the trial team, a local healthcare profession­al, or a research nurse, andaskedto­consideren­rolling in the study.

Alternativ­ely, anyone who meets the eligibilit­y criteria can sign up to take part in the study at www.panoramict­rial. org

People can join the study if they are aged 50 and over, or between 18 to 49 years with underlying health conditions thatmaketh­emclinical­lymore vulnerable. All participan­ts also need to have had a positive COVID-19 test and be within five days of the onset of symptoms.

Prof Nick Lemoine, medical director at the National Institute for Health Research Clinical Research Network said: “When taken in the earliest stages of infection, these ground-breaking, purposedes­igned, COVID-19 antiviral treatments hold the potential to greatly improve outcomes for patients most at risk from the disease.

"As orally-administer­ed treatments,designedto­betakenath­omesoonaft­ertheonset of symptoms, the drugs work by disrupting and preventing the virus from multiplyin­g inside the body.”

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