The Chronicle

How a gift in your Will to Cancer Research UK helps pioneering North East research

RESEARCH IS ESSENTIAL FOR NEW TESTS TO HELP THE 16,700 PEOPLE DIAGNOSED WITH CANCER EACH YEAR IN THE NORTH EAST

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AROUND 16,700 people are diagnosed with cancer each year in the North East, highlighti­ng how essential research is to find gentler treatments and new tests.

Many research projects across the UK benefit from the generosity of people leaving a gift to Cancer Research UK in their Will.

Dr Debbie Hicks is a Newcastle University Research Fellow of Molecular Survivorsh­ip. Her main area of research is childhood brain tumours, working to improve outcomes for survivors of medullobla­stoma and other childhood cancers.

Dr Hicks said: “Medullobla­stoma is the most common malignant childhood brain tumour.

My work involves understand­ing the ‘molecular pathology’ of the disease – elucidatin­g the molecular alteration­s important in the developmen­t and progressio­n of medullobla­stoma, and in its response to treatment.”

“Whilst nowadays 6070% of patients survive their medullobla­stoma diagnosis, the aggressive nature of cancer treatment can affect survivors’ quality of life.”

“Perhaps the most devastatin­g impacts of the reduced quality of survival that follows brain tumour treatment are the neurocogni­tive deficits (IQ, attention, executive functions, etc) which render childhood survivors feeling ‘left-behind’ compared to their peers and at a disadvanta­ge entering their teenage and adult years.”

“My research aims to not only promote survival but to also reduce the disease and burden of current treatments in medullobla­stoma and other childhood cancer survivors.”

“Cancer Research UK’s funding is vitally important to our work. I was part of a team that was supported by Cancer Research UK Programme Grant funding, without which we would have not been able to make the strides we have in identifyin­g the disease and the extent of the risks it poses that are now transition­ing into medullobla­stoma clinical trials.”

“Contempora­ry biomarker-driven clinical trials are either about to open, or currently accessible, to every child with medullobla­stoma across Europe, supported by our real-time clinical and molecular testing systems.”

“On the back of this experience, I was able to establish my own programme of research; Cancer Research UK are supporting this by funding a PhD student in my group, thereby nurturing the careers of the next generation of researcher­s.”

“We are passionate about the work we do and its power to help children with cancer. To be given the opportunit­y to put this passion into practice is a privilege and a great personal honour.”

Gifts in Wills account for over a third of its life-saving research. Without this, Cancer Research UK simply would not be able to undertake all the vital research it does which could one day beat cancer.

The charity has played a role in developing 8 of the world’s top 10 cancer drugs and it helped prove the link between tobacco and cancer.

By leaving a gift in your Will, you can help keep the amazing breakthrou­ghs coming and support this life-changing work. You could transform lives for generation­s to come.

Together we will beat cancer

 ??  ?? Dr Debbie Hicks is a Newcastle University Research Fellow of Molecular Survivorsh­ip
Dr Debbie Hicks is a Newcastle University Research Fellow of Molecular Survivorsh­ip
 ??  ?? Dr Debbie Hicks’ main area of research is childhood brain tumours
Dr Debbie Hicks’ main area of research is childhood brain tumours

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