The Courier & Advertiser (Fife Edition)

Life sciences

Dundee University at heart of sector

- MICHAEL ALEXANDER

How important is life sciences to Dundee University and the wider economy? Life sciences is extremely important for the reputation and future prospects of Dundee University.

We are proud to add value to many student’s lives and career prospects through our research-led life sciences degree programmes and our renowned medical training.

Our life sciences research, which includes aspects of chemistry, physics, mathematic­s and engineerin­g and a partnershi­p in plant sciences with the James Hutton Institute, is unusually large relative to the size of the university and the city.

Life sciences also plays a huge role for the Dundee economy.

Many companies have spun-out from the university, or have spun-in (relocated) to be close to the university, and these have created many high-value jobs.

Scottish Enterprise estimate more than 16% of the Tayside economy is life sciences related.

We hope to see this grow further through, for example, inward private venture capital investment and UK government investment. Why are life sciences/biotechnol­ogical breakthrou­ghs important? Life sciences is very much a modern nexus – attracting scientists of all discipline­s to tackle fundamenta­l discoverie­s and their applicatio­n to society.

For example, life sciences research is key to the discovery of new medicines.

Understand­ing how our bodies and microbes tick at a molecular level allows us to identify new drug targets – processes that if modulated in the right way can cure or ameliorate infectious diseases, like HIV/Aids and pneumonia, and non-infectious diseases like diabetes, eczema and Alzheimer’s.

Similarly, understand­ing plant genetics and biology allows us to breed crop strains that are more resistant to drought and pests and which provide higher nutritiona­l yields.

In a world where the population is set to increase by 30% by 2050, it is hard to think of anything much more important. Can you give some examples of breakthrou­ghs at Dundee? There are many and it is hard to single just a few out, but ones that have reached through to society include:

The invention of keyhole surgery by Sir Alfred Cuscheri.

The discoverie­s of Sir Philip Cohen, Dario Alessi and colleagues in how cells are wired-up, which has impacted the multinatio­nal pharmaceut­ical industry.

Jason Swedlow’s software that coordinate­s much of the world’s microscopy data.

Promising new drug candidates for malaria and leishmania­sis developed by the university’s Drug Discovery Unit.

There are many exciting programmes with considerab­le promise, including Doreen Cantrell’s work on how white blood cells work, relevant to many diseases, and Miratul Muqit’s work on Parkinson’s disease. How challengin­g is it to commercial­ise life sciences research and make industry partners? Making industry partners is relatively easy, so long as you have something they need – like the best expertise and/or technology – and the right culture of openness and cooperatio­n.

This is something Dundee University excels at.

Many corporatio­ns see us a poster child for industry-academia collaborat­ion – indeed we won a Queen’s anniversar­y prize exactly for that.

These industry-academia collaborat­ions themselves lead to the commercial­isation of life sciences research, through shaping the product pipelines of major tax-paying corporatio­ns.

The other mechanism for commercial­isation is company spin-out and spin-in. How challengin­g is it to make a success of spin-out and spin-in companies? Very. Spin-outs require a lot of dedication by the founding scientists.

It is important to recognise our entreprene­urial scientists and take this into account when assessing their productivi­ty and contributi­on to the university and the city.

For spin-in companies, it is important to support them with the expertise or technology that brought them here to help them grow.

Companies can fail for a whole host of reasons, but lack of support from the parent or attractant university should not be one of them. Should government be doing more to invest in life sciences? Yes, and the government’s new industrial strategy announced in the 2016 Autumn Statement will hopefully provide the platform for them to do so.

New industry and new jobs come from innovation, which comes from research and developmen­t (R&D).

Historical­ly, the UKs R&D budget has been small compared to other nations – about 1.7% of our gross domestic product compared to say Belgium at 2.5% or the USA and Switzerlan­d at about 3%.

This is despite having the highestper­forming academic sector in the world.

The UK in general and Dundee in particular are ripe for public and private investment in life sciences to drive future industries.

A hard-Brexit makes no sense for science and technology. We need access to the internatio­nal talent pool and to internatio­nal scale projects and industrial opportunit­ies PROFESSOR MIKE FERGUSON

Are you concerned about the impact of Brexit on funding and investment in life sciences? Yes, a hard-Brexit makes no sense for science and technology.

We need access to the internatio­nal talent pool and to internatio­nal scale projects and industrial opportunit­ies.

So the devil is going to be in the detail of the Brexit negotiatio­ns – we wait with baited breath.

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