The Daily Telegraph

Astrazenec­a in $400m deal for Parkinson’s treatment

- By Iain Withers

ASTRAZENEC­A has struck a deal worth up to $400m (£309m) to sell rights to a promising treatment for Parkinson’s disease, as the FTSE 100 giant presses ahead with offloading non-core drug assets to raise funds for its priority pipeline in areas such as cancer.

The British firm has agreed a commercial tie-up with Japanese drugs company Takeda, under which the two companies will jointly develop the antibody therapy MEDI1341 for degenerati­ve neurologic­al conditions including Parkinson’s. It will enter Phase One clinical trials later this year. The tie-up is the latest of a string of deals by Astrazenec­a this summer to raise funds for its core areas, including selling the commercial rights to migraine treatment Zomig and beta-blocker Seloken, raking in a combined £450m.

Astrazenec­a, led by chief executive Pascal Soriot, has been prioritisi­ng areas including finding cures for cancer and heart disease, whereas Takeda is a neuroscien­ce specialist. Takeda will pay Astrazenec­a up to $400m and thereafter the firms will equally share future developmen­t and commercial­isation costs, as well as future revenues. Astrazenec­a will work on Phase One developmen­t, with Takeda leading on clinical developmen­t.

Astrazenec­a has separately agreed a deal with Boston-based Berg to use artificial intelligen­ce in the search for Parkinson’s disease treatments.

The firm has also received approval from US regulators for expanded use of its breast cancer drug Faslodex. The news is a boost to Astrazenec­a’s oncology business, after a bad initial readout from a lung cancer drug trial wiped £10bn from its market value in a single day last month. Astrazenec­a shares closed down 7p at £44.92.

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