The Daily Telegraph

Why Commonweal­th countries are the key in the battle to beat malaria

Under British leadership, we are making ambitious commitment­s to reverse a sudden rise in malaria

- Bill Gates

Since I started my second career as a philanthro­pist almost 20 years ago, I have seen more suffering than I ever expected. One of the worst things I have ever seen, years ago in Tanzania, is a child having seizures from cerebral malaria. I didn’t know if he would survive. I did know that, even if he did, his brain developmen­t would be impaired.

The fact that the world has saved millions of children from that kind of suffering is a great achievemen­t. It’s a testament to our collective persistenc­e and ambition. I don’t use superlativ­es lightly. But progress against malaria has been one of the most impressive successes in global health in this generation.

In 1999, almost one million people died of malaria. Since then, malaria funding has increased tenfold. This increase has financed highly effective drug treatments, rapid diagnostic tests, long-lasting indoor insecticid­e sprays, and insecticid­e-treated bed nets. Such innovation­s have saved almost seven million lives and eliminated malaria in 18 countries. Half the world is now malaria-free.

Much of this progress has been thanks to the British. As investors in the Global Fund to Fight Aids, Tuberculos­is and Malaria, and through bilateral aid and research and developmen­t funding, they have helped reinvigora­te the fight.

The strength of British scientific innovation in malaria is among the best in the world. More than a century after Sir Ronald Ross discovered that mosquitoes transmit the malaria parasite, British R&D is still giving us the tools we need to defeat malaria. It has put us on the path to end malaria for good – helping to build a safer, more secure and more prosperous world for all of us.

But a child still dies from malaria every two minutes, every day. More than 200million people still suffer from the disease every year. And in 2016, for the first time in years, the number of malaria cases in the world went up. This is not a blip. It is not noise. It is a signal. Malaria is fighting back.

Much of our current effort is going toward replacing worn-out nets and re-spraying houses, which means that we are using a significan­t proportion of the money and effort we have just to keep up. The nets, sprays, and drugs also aren’t working as well as they used to. Resistance to the insecticid­es that drove numbers of cases and deaths down is now widespread. We are also seeing pockets of resistance to the most important drug combinatio­ns we use to treat malaria. And human migration is continuall­y importing the disease from high burden to lower burden areas. In short, we have reached the point of diminishin­g returns from our current strategy.

Commonweal­th countries and their leaders are on the front line in the fight against malaria, with 90 per cent of Commonweal­th citizens living in malaria-affected countries. That’s why today’s Malaria Summit is so important, and why we are having it here in London as the leaders of the Commonweal­th are gathering together. There aren’t many organisati­ons that bring together countries from all over the world on an equal footing to talk about a shared vision for the future. That shared vision, history, and equal partnershi­p make the Commonweal­th a powerful engine of progress.

This week, Commonweal­th leaders can write the next chapter in the story of our fight against malaria by taking up the ambitious goal of halving the burden in five years, saving 650,000 lives and preventing 350million cases. It will take new funding, high-quality data to track progress, better disease surveillan­ce to identify malaria outbreaks, and innovation to develop the new tools we need to fight a disease that is trying to outsmart us.

The good news is that, unlike 15 years ago, when we were emerging from decades of stagnation, innovation is already producing results in prevention, detection, and treatment. And British scientists are leading the way.

First, on prevention, the IVCC in Liverpool has partnered with crop protection companies to develop new insecticid­es. Secondly, on detection, highly sensitive rapid diagnostic­s can detect malaria in people who aren’t sick and don’t know they are harbouring the parasite. Thirdly, on treatment, GSK, the British pharmaceut­ical company, is developing a single-dose regimen to cure people who have the relapsing form of the disease.

Thanks to new drugs developed through the Medicines for Malaria Venture, we also have more options for managing severe cases. And, for the first time, we now have an approved malaria vaccine, also developed by GSK, to be introduced later this year.

I’m particular­ly excited about the potential of gene drive, a method of mosquito control that can make mosquitoes infertile or prevent them from carrying the malaria parasite. Scientists at Imperial College in London are at the forefront of this promising work. We have a long way to go before the technology is perfected, but it is the kind of breakthrou­gh we need, while deploying other proven tools in the short run.

Yesterday, the Prime Minister reaffirmed the UK’S commitment to invest £500million each year over the next three years in the fight against malaria. As part of this, she announced a further £100million to the Global Fund to match new funding raised from private donors. Today, leaders of more than a dozen malaria-affected Commonweal­th countries will be making substantia­l pledges to fight the disease in their own countries.

The private sector is stepping up, too. And my own foundation will commit an additional £700million – including a £50 million contributi­on partly to match the UK’S new commitment to the Global Fund – to the fight against malaria over the next five years. In total today, the global community will commit over £2.7billion of funding and accelerate­d innovation to save lives and put us on the path to ending malaria forever.

These ambitious commitment­s are evidence of the power, influence and optimism of the Commonweal­th. Together with the applicatio­n of new and innovative science, we are moving one step closer to a day when no child will go through what I saw in that hospital in Tanzania ever again.

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