The Daily Telegraph

Doctors alerted amid claim 90pc penicillin allergies misdiagnos­ed

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DOCTORS have been urged to check patients for false penicillin allergies to stop the spread of deadly MRSA after research showed 90 per cent may have been wrongly diagnosed.

The National Institute for Health and Care Excellence (Nice) said the issue may also be contributi­ng to the spread of antibiotic resistance.

It said that some people believe they are allergic to the antibiotic because it gave them a rash as a child – which is different to a true penicillin allergy.

This has led to people having a false recording of a penicillin allergy held on their medical notes for decades, it added.

The health body is urging healthcare staff to discover whether their patients have a true allergy by using its guide- lines. By doing so, they could help stop the spread of MRSA – a type of bacteria that is resistant to several widely used antibiotic­s – and antimicrob­ial resistance.

Nice said that people who incorrectl­y believe they are allergic to penicillin are unnecessar­ily put at an increased risk of developing MRSA or Clostridiu­m difficile – a bacteria that can infect the bowel and cause diarrhoea. Hundreds of people die every year from MRSA, latest figures show.

It comes as a study published earlier this year found that people with a documented penicillin allergy had an increased risk of MRSA and C difficile.

They were found to be 69 per cent more likely to develop MRSA and 26 per cent more likely to develop C difficile, according to the study of nearly 300,000 patient records.

Patients with a penicillin allergy are more likely to be treated with broad spectrum, non-penicillin antibiotic­s, which may have fuelled the increased risk. Nice said the findings emphasise the need for healthcare staff to check that only bona fide penicillin allergies are recorded.

Past research has found that around one in 10 people have a documented penicillin allergy, but it is thought that fewer than 10 per cent of these people have a “true” allergy to the antibiotic.

Professor Gillian Leng, deputy chief executive of Nice, said: “Lots of people think they are allergic to penicillin because it gave them a rash when they were a child, their mum or dad told them they were allergic and it has stayed in their notes for decades.

“That is a very different thing to having a true penicillin allergy, which can result in a life-threatenin­g anaphylact­ic reaction.

“If healthcare staff use Nice guidance to distinguis­h properly between the two, that could help stop the spread of both MRSA and antimicrob­ial resistance.”

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