The Daily Telegraph

Why slimmers are thwarted by the science of losing weight

- By Sarah Knapton SCIENCE EDITOR

DIETING is hard because weight loss sets off an evolutiona­ry “red flag” in the brain which triggers hunger cravings, a Cambridge University geneticist has warned.

Giles Yeo told the Hay Festival that losing weight was meant to be difficult because humans were hardwired to maintain a constant size for the best chance of survival.

Some people find it harder to diet because their genes cause their brain to underestim­ate body weight from signals released by fat cells, causing the body to make hunger hormones.

“Losing weight ain’t easy, and it isn’t meant to be,” said Mr Yeo. “It doesn’t matter how skinny you are, your brain perceives weight-loss as a big red flag, a decrease in your chances of survival.

“The moment you lose weight your brain...drags you kicking and screaming back up to the weight you were.”

Mr Yeo said the only way to lose weight was to follow the first law of thermodyna­mics: energy cannot be created or destroyed. People must eat more than they burn to gain weight, and burn more than they eat to lose weight.

“It’s physics,” he said. “Anyone who is selling you an effortless way to lose weight is lying.”

No foods should be off limits, Mr Yeo said, unless there was a clinical reason

not to eat them. Gluten or milk were fine for 95 per cent of white Europeans. Whereas most mammals do not consume milk after childhood, humans developed a mutation, after the birth of agricultur­e and animal domesticat­ion about 7,500 years ago, that allowed the digestion of lactose in adulthood.

Instead of cutting out food groups, he suggested eating a little of everything.

“Moderating is intensivel­y boring, and it’s very difficult,” he said. “People have removed all kinds of stuff from their diet . . . They are now naming things gluten free which never had gluten to begin with.”

He advised dieters to stop counting

calories because with many foods all the calories were not absorbed. People absorbed only about 70 per cent of the calories in meat, which was why diets that cut out carbohydra­tes were effective. Similarly vegan diets worked because plants were bulky, Mr Yeo said.

“The caloric availabili­ty from vegan food is lower than everything else. In 29 days on a vegan diet I lost 10lb while eating as much as I wanted and my blood cholestero­l dropped 12 per cent.

“Except let’s look at why. A plantbased diet is very bulky. So what actually happened is I ended up eating less calories. My cholestero­l level dropped because I lost weight but largely because I gave up saturated fats.”

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