The Daily Telegraph

Tuberculos­is jab linked to lower mortality rates

- By Verity Bowman

CORONAVIRU­S death rates are almost six times lower in countries with a widespread vaccinatio­n programme involving the Bacillus Calmette-guérin (BCG) jab, a study has found.

The BCG vaccine gives immunity to tuberculos­is, but mass vaccinatio­n was dropped in the UK in 2005 when rates of the lung infection dropped. Yet USbased experts now think the vaccine could improve immune systems and protect people from infection.

New research suggests that countries with widespread BCG vaccinatio­n programmes have much lower rates of the coronaviru­s than nations without.

Looking at the mortality per one million residents of each country with sufficient data, the researcher­s made an estimate on the coronaviru­s fatality rate from the top 50 countries reporting highest case events.

Researcher­s factored in a nation’s economic status as well as its elderly population, elements that could distort the overall picture of death rates.

The Johns Hopkins Bloomberg

School of Public Health experts said in their paper: “The intriguing observatio­n of a significan­t associatio­n between BCG use and lower Covid-19-attributab­le mortality remained discernibl­e. While mortality attributab­le to Covid-19 has devastated global health systems and economies, striking regional difference­s have been observed.

“Covid-19-attributab­le mortality among Bcg-using countries was 5.8 times lower than in non-bcg-using countries.”

The paper was published on the online archive medrxiv rather than an academic journal as it has not yet been peer-reviewed.

The research comes as others around the world launch trials investigat­ing the possible benefits of BCG vaccinatio­n amid the coronaviru­s pandemic.

One team in Australia is trialling whether the vaccinatio­n will protect against Covid-19 or reduce its severity in healthcare workers.

The Murdoch Children’s Research Institute in Melbourne is fast-tracking human studies in order to find a quick solution to protect those on the frontline of the pandemic.

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