The Daily Telegraph

Obese Covid patients 40pc more likely to die

Excess weight one of the most deadly risk factors because fat cells compound inflammati­on, study finds

- By Laura Donnelly Health editor

Obese people hospitalis­ed with coronaviru­s are almost 40 per cent more likely to die than other patients, the first major study in Britain has found. Researcher­s said the findings also suggest that for patients who end up in hospital with Covid-19, the virus is just as deadly as Ebola. The research on almost 17,000 hospital cases found that excess weight is one of the most deadly risk factors. The average age of coronaviru­s patients treated in hospital was 72.

OBESE people hospitalis­ed with coronaviru­s are almost 40 per cent more likely to die than other patients, the first major study in Britain has found.

Researcher­s said the findings also suggest that for patients who end up in hospital with Covid-19, the virus is just as deadly as Ebola.

The research on almost 17,000 cases admitted to hospital found that excess weight is one of the most deadly risk factors.

The study, led by Liverpool University and involving Imperial College London, which involved 166 UK hospitals, found the average age of coronaviru­s patients admitted to hospital was 72.

Overall, 49 per cent of patients have so far been discharged alive, while 33 per cent have died and 17 per cent were still receiving care when the results were reported.

Chief investigat­or Prof Calum Sem- ple, professor in child health and outbreak medicine at the University of Liverpool, said Covid-19 was an “incredibly dangerous disease”.

He said: “Crude hospital case fatality rate is of the same magnitude as Ebola. And people don’t get this.

“If you come into hospital with Covid disease and you’re sick enough to be admitted, crude case fatality rate is sitting somewhere between 35 and 40 per cent.

“And that’s the same case crude case fatality rate for someone admitted to hospital with Ebola.”

Some 60 per cent of those admitted were male, and women were 20 per cent more likely than men to survive.

The research, which has yet to be peer-reviewed, found that almost half of cases lacked any underlying health condition or extra risk such as obesity.

But when patients admitted to hospital were obese, their risk of death rose by 37 per cent. Prof Semple said those who were obese with a body mass index (BMI) over 30 “do particular­ly badly from Covid disease, so they’re more likely to go on to the intensive care units and to go on to die”.

There were many reasons why obese people may have a “very tough ride” if they catch the virus, he said.

“Nobody who is a big person is just a big person in isolation.

“But [the] disease will cause problems in their lungs and hearts and kidneys for complex reasons, because fat cells secrete chemicals that essentiall­y increase the inflammato­ry state of the body.”

He said it was also striking that the disease affected men much more than women, with the gap widening with age.

Those with dementia had death rates 39 per cent higher than other patients, while heart disease patients faced a 31 per cent increased risk. Death rates in patients admitted over the age of 80 were 14 times as high as those among the under-50s. And risks for those in their 70s were 10 times that of those under 50.

Prof Semple praised the majority of Britons for sticking to the lockdown.

But he said: “Still we see isolated egregious examples of selfishnes­s, where people think it’s OK to meet up in the park and share a four-pack of beer, and I’ve seen it happen.

“And the attitude… particular groups of younger people are taking is, ‘All right Jack, this doesn’t bother me, why should I be worried?’ They just don’t understand that they’re just as likely to catch it and transmit it. And that will affect the rest of society.”

The study tracked 16,749 patients admitted to hospital with Covid-19 in England, Scotland and Wales between 6 February and 18 April this year.

Just 2 per cent of patients were under 18, including 1.1 per cent under five.

‘Hospital case fatality rate is somewhere between 35 and 40 per cent – that’s the same as for someone admitted with Ebola’

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