The Herald

Spicy curries ‘help to fight colon cancer’

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EATING curries could help battle colon cancer, according to new research.

Curcumin, the active ingredient in turmeric – one of the basic spices used in many curries – stopped cancer cells from spreading .

But when it was combined with silymarin, which is derived from the common herb milk thistle, the effect was even more impressive.

The researcher­s, writing in the Journal of Cancer, studied a line of colon cancer cells in a laboratory model.

They found treating the cells initially with curcumin, then with silymarin was more effective in fighting cancer than treating the cells with either phytochemi­cal alone.

Dr Uthayashan­ker Ezekiel, associate professor of biomedical laboratory science at Saint Louis University, said: “The combinatio­n of phytochemi­cals inhibited colon cancer cells from multiplyin­g and spreading.

“In addition, when the colon cancer cells were pre-exposed to curcumin and then treated with silymarin, the cells underwent a high amount of cell death.

“Phytochemi­cals may offer alternate therapeuti­c approaches to cancer treatments and avoid toxicity problems and side effects that chemothera­py can cause.”

Dr Ezekiel warned the research is a preliminar­y and more study will be required before scientists know if the compounds are an effective treatment for people who have colon cancer.

He saw promise in using the phytochemi­cals to help prevent colon cancer.

Scientists next would need to study how the curcumin and silymarin impact the actions of molecules that cause cells to change.

Then the compounds would be studied in an animal model before clinical trials take place on humans.

Dr Ezekiel said: “We still have much to learn, and for now, it’s so much safer to add a little spice to your diet and get your curcumin from foods that contain turmeric rather than taking high doses of the compound.”

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