The Jewish Chronicle

Humane scientist with full life outside the laboratory

Aaron Klug: A Long Way From Durban

- By Kenneth C Holmes

Cambridge University Press, £20

THIS IS a biography of a genius. Sir Aaron Klug FRS OM is not only a Nobel Prizewinni­ng scientist but also a polymath: linguist, lover of the arts, mountainee­r, an astute diplomat and a man with an extraordin­ary life story.

Author Kenneth C Holmes, FRS, was a long-term collaborat­or of Klug’s from his early years at Birkbeck College and subsequent­ly at the Laboratory of Molecular Biology in Cambridge. If, mistakenly, Holmes assumes that all readers of the book will be scientific­ally literate, and includes lengthy and chal- lenging chapters of detailed scientific informatio­n, he also does justice to Aaron Klug’s’s extraordin­ary journey from Zelva, the Lithuanian shtetl where he was born, to Cambridge, via Durban, where the family emigrated and which was recollecte­d later by Klug as a “relatively sleepy town in sub-tropical surroundin­gs.” Included, too, are unforgetta­ble stories of scientists working in attics, colposted laborating to produce life-changing discoverie­s, confrontin­g the shocking myopia of the Thatcher government in relation to science education and research funding — and carrying on.

Memorable are chance encounters that transforme­d Klug’s work, for example a meeting with Rosalind Franklin, who was then working on the tobacco mosaic virus and would become a vital colleague and loved family friend.

“Her beautiful X-ray photograph­s fascinated me,” Klug noted, “and I was able to interpret some pictures which had apparently anomalous curved layer lines, in terms of the splitting which occurs when the helical parameters are non-rational. From then on my fate was sealed.” (Les Prix Nobel, Nobel Foundation, Stockholm, 1983)

Equally random and equally crucial was his move from Johannesbu­rg — where he did his first degree — to Cape Town. Having joined Hashomer Hatzair at Witwatersr­and, Klug was to Cape Town to prop up the failing branch.

Fortunatel­y, he was able simultaneo­usly to fill a post as a demonstrat­or in physics at Cape Town University, which led to an MSc and a graduate scholarshi­p at Trinity College, Cambridge. Aaron Klug’s private life also blossomed in Cape Town. It was where he met musician and radical dancer, Liebe Bobrow, whom he married.

She occupies a key place in Holmes’s narrative. When her husband became president of the Royal Society, she set about giving it a human face.

While science and outstandin­g scientists — Francis Crick, James Watson, Max Perutz, Sydney Brenner, John Finch, Alan Cormack Godfrey Hounsfield and Sir Alan Fersht, to name but a few — fill the pages, they also reveal Klug’s humanity and unyielding intellect. He has no time for “wrongheade­dness” whether in science or politics, but puts his case with uncompromi­sing clarity and thoughtful­ness: witness the argument against misogyny at Peterhouse College, Cambridge.

Ironically, Aaron and Liebe were unable to make a life in Israel as they had initially wished.

In 1950, the Weizmann Institute rejected the young scientist. Notwithsta­nding this, Klug has made an outstandin­g contributi­on to the country where his elder son Adam settled and raised a family and very sadly died prematurel­y.

Holmes records that, at the time of writing, typically of a remarkable family, Yoel, Aaron’s oldest grandchild, elder son of Adam and his wife Debbie, was working for his doctorate at the Weizmann. It is such stories that make this excellent biography irresistib­le.

Memorable chance encounters

his work

Jane Liddell-King is a freelance writer

 ??  ?? Aaron Klug: unyielding intellect
Aaron Klug: unyielding intellect

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