The Mail on Sunday

Breast milk... the ‘accidental’ cure for cancer

- By Stephen Adams HEALTH CORRESPOND­ENT

BREAST milk is being used to fight cancer after scientists accidental­ly discovered it contains a substance that kills tumour cells.

Trials in patients with bladder cancer have already yielded promising results and researcher­s believe the compound breast milk contains – nicknamed Hamlet – will also help tackle bowel cancer and cervical cancer.

They also say it homes in on cancer cells while leaving healthy cells unharmed – so it has none of the debilitati­ng side effects of chemothera­py.

Professor Catharina Svanborg, who made the initial discovery, said last night: ‘There’s something magical about Hamlet’s ability to target tumour cells and kill them.’

She said human breast milk contained a protein called alphalacta­lbumin, which is transforme­d into a cancer-fighting agent when in the gut.

Prof Svanborg, an immunologi­st at Lund University in Sweden, made the chance discovery that the substance kills tumour cells when working on antibiotic­s.

She said: ‘We were looking for novel antimicrob­ial agents, and new breast milk is a very good source of these. During one experiment we needed human cells and bacteria to be present, and we chose human tumour cells for practical reasons.

‘To our amazement, when we added this compound of milk, the tumour cells died. It was a totally serendipit­ous discovery.’

The substance attacks cancer cells in numerous ways – first evading the cell’s outer defences, then targeting the ‘power station’ mitochondr­ia and the ‘instructio­n manual’ nucleus. These actions cut off the cell’s energy source and ‘programme’ it to commit suicide, in a process called apoptosis.

Early trials in patients with bladder cancer show those injected with Hamlet start shedding dead tumour cells in their urine within days.

A full-scale trial pitting Hamlet against a placebo ‘dummy drug’ is now planned.

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