The Mail on Sunday

Memory test that helps stop bipolar disorder

- By Erica Crompton

A SIMPLE computer test could help prevent bipolar disorder in those who have a high genetic risk of developing the condition.

Pioneering research has shown that the task can effectivel­y ‘rewire’ the brains of those living with the mood disorder.

During the test, patients were asked to look at emotional photograph­s – such as angry expression­s or images of mutilated bodies – and then memorise the order of them.

It is widely acknowledg­ed that people whose parents or siblings suffer f rom bipolar disorder – a serious mental illness affecting one per cent of the UK population – are between four and six times more likely to develop the condition themselves.

In the new study, researcher­s at the Icahn School of Medicine at Mount Sinai in New York conducted experiment­s involving patients with a family history of bipolar disorder.

Over a three- week period, each patient was asked t o spend 20 minutes a day looking at the pictures. They later underwent an MRI scan to measure the difference­s in brain connectivi­ty and structure after the experiment.

The scans revealed that after the photo-memorising task, participan­ts’ brain wiring was altered and brain connectivi­ty was improved, particular­ly in areas typically affected by bipolar disorder.

Lead researcher Sophia Frangou said: ‘If participan­ts engage in these tasks for about 20 minutes per day, we see a restructur­ing of the brain in a way that could be helpful and is cost-effective.’

She added: ‘While we see an effect after three weeks, we don’t know how long it will last.

‘People may need booster sessions t o achieve l ong- t erm, preventa - tive effects.’

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