The Mail on Sunday

Cholestero­l jab ‘can slash heart att ack risk by a quarter’

- By Stephen Adams HEALTH CORRESPOND­ENT

A CHOLESTERO­L-lowering jab has been shown to reduce the chance of a heart attack by up to a quarter.

Two years ago drugs watchdog Nice approved alirocumab for treatment on the NHS for people who could not tolerate statins and those with a family history of high cholestero­l. Now scientists have found that the £4,400-a-year treatment cuts the odds of a heart attack by up to 24 per cent.

The findings are from a trial of 19,000 patients, results of which were presented at a US cardiology conference last month.

All the patients involved had experience­d a heart attack or another serious heart problem before. The trial found that, overall, alirocumab – also known by its brand name Praluent – cut the risk of a ‘major adverse cardiovasc­ular event’ by 15 per cent. But among those with the highest cholestero­l levels, who were given Praluent together with high strength statins, it cut the risk by 24 per cent.

The drug, taken by injection every two or four weeks, is a joint developmen­t between firms Sanofi and Regeneron.

Dr George Yancopoulo­s of Regeneron said many people who had experience­d a first heart attack had ‘an urgent need’ to reduce their cholestero­l levels. He said: ‘In this trial, such patients who received Praluent on top of maximally tolerated statins had important reductions in their risk.’

Newspapers in English

Newspapers from United Kingdom