The Mail on Sunday

Is your Sunday roast beef really as bad as smoking? Don’t be ridiculous!

- By Jo Macfarlane

THE first bite of a bacon butty in the morning. A lunch of perfectly moist roast beef, paired with towering piles of crispy roast potatoes and doused in homemade gravy. For many, these are key ingredient­s to a perfect Sunday.

But in recent years, mounting evidence has suggested these simple pleasures, enjoyed too often, could wreak havoc on our health.

A series of studies have raised the alarm over red meat, particular­ly processed meat, linking it to bowel and colon cancers.

In 2015, the Internatio­nal Agency for Research on Cancer classified processed red meat – including sausages, bacon, ham and pâté – as a ‘definite’ cause of cancer, alongside cigarettes.

The World Cancer Research Fund advises eating ‘little, if any’ processed meat such as bacon and sausages, and only ‘ moderate’ amounts of beef, pork and lamb.

The NHS, too, recommends no more than 70g of cooked or processed meat every day – equival ent t o one- and- a- half pork sausages, two rashers of bacon or one third of an averagesiz­ed sirloin steak. But will busting that limit put us on a fast-track to cancer? The answer is probably not. The current advice stems from a 2010 report by the Government’s Scientific Advisory Committee on Nutrition.

Scientists analysed evidence provided by hundreds of studies that had looked at the relationsh­ip between meat and cancer since the 1970s, involving millions of participan­ts around the world.

Their conclusion, based on the analysed research, was that we should err on the side of caution and stick to 70g daily.

But many of the research included was flawed, leading even the committee itself to state: ‘Although a number of plausible biological mechanisms have been proposed to explain the associatio­n between red meat and colorectal cancer risk, none is supported by convincing evidence.’

Some studies did not distinguis­h between the effects of eating red meat – a steak, mince or a leg of lamb – and processed meat.

Others drew on dietary habits from outside of the UK where meat production – and ingredient­s in products – can be vastly different.

And then there is the problem in the way the evidence is gathered.

Diet studies rely on participan­ts rememberin­g and then reporting what they’ve eaten over the course of a month or year – which is, for obvious reasons, unreliable.

And, most diets contain a huge variety of foods. So even after making complicate­d statistica­l adjustment­s, it is difficult to determine how any one thing has an effect.

Other studies have shown that, for instance, men who eat a lot of meat are also less likely to eat vegetables and fruit, and more likely to engage in other, unhealthy behaviours such as smoking and drinking alcohol.

RED MEAT CAN POSE A RISK – BUT IT’S SMALL

SO ARE all the concerns simply misguided, nannying rubbish? Well, not entirely. There is some legitimate concern over the link between processed red meat – bacon, ham and such like – and the risk of bowel cancer. The issue is thought to lie with chemicals called nitrates that are added to meat products in order to lengthen their shelf life. Once inside the stomach, these react with bacteria to form nitrosamin­es, which are known to be involved in the developmen­t of bowel cancers.

A Cancer Research UK study of half a million adults, published in the European Journal Of Epidemiolo­gy in April, found that those who ate the most processed meat were 20 per cent more likely to get bowel cancer than those who ate the least.

But it is worth putting this into context. Last year, Tom Sanders, professor of nutrition and dietetics at King’s College London, told us: ‘Only one in a hundred cases of colorectal cancer is said to be related to processed red meat compared to 64,500 cancers a year caused by smoking.’

World Health Organisati­on data shows the colorectal cancer risk is 1.18 times higher if you eat 50 grams of processed red meat every day – roughly two slices of bacon. But the risk of any cancer is 40 times higher if you smoke, and 70 times higher for those who

Mediterran­ean diets high in fresh fish, nuts, fruit, vegetables and olive oil can cut the risk of breast cancer

smoke and drink. It all means that on a population level, if every person eats lots of processed meat, it would result i n a significan­t number of extra cancer cases. But for an individual, the risk is small.

And this is precisely the point of the highly controvers­ial study on meat published last week.

Although the research, published in Annals Of Internal Medicine, concluded that eating just under two bacon rashers every day for most of your l i fe is l i kely to increase the risk of colorectal cancer, the evidence isn’t strong enough to warrant cutting back significan­tly. The benefits of cutting back – the scientists suggest – are ‘trivial’.

The report recommends that eating up t o four portions of red or processed meat every week poses no risk – contrary to almost every other guideline from official health bodies around the world.

Pharmacolo­gist David Colquhoun, a professor at University College London, adds: ‘We have no absolute proof t hat meat causes cancer.

‘To get that, we’d need to lock people away on a closed ward and feed them a high meat diet for their entire lives to see what happened to them.’

Prof Colquhoun says the risk posed by red meat specifical­ly has decreased as the evidence has mounted over the years. ‘The EPIC study in 2013, which followed nearly half a million people over more than 12 years, found red meat posed no detectable risk of death. The increased risk was about two per cent.’

There are now important questions over whether the evidence from studies – however weak – might point to there solely being a risk from processed meat.

Writing in 2017 in the British Medical Bulletin, Dr Ian Johnson, emeritus f el l ow at Quadram Institute Bioscience, said: ‘The evidence for an associatio­n with colorectal is stronger for processed meat than for red meat, and indeed some still argue that the evidence in relation to red meat remains too weak and inconsiste­nt to justify a conclusion.’ So, riskaverse types might simply choose to neglect the odd sausage or slice of bacon. But forgoing your Sunday roast or the odd bacon sandwich? That’s just silly.

DON’T STOP ENJOYING YOUR CRISPY ROASTIES

THE gnarly, crisp ridges of a roast potato are, according to many, the best part of a Sunday roast.

For many, it’s a case of the browner, the better.

But a preference for overdone roasties could leave you privy to ‘toxic cancer agents’, some reports would have you believe. In 2017, following a series of studies, the Food Standards Agency warned of the possible risks involved with over-cooking foods, particular­ly those high in starch.

The concerns related, specifical­ly, to roasted potatoes, burnt toast and frozen chips.

The watchdog encouraged us to ‘go for golden’ after research found high levels of the chemical acrylamide – a known carcinogen – in foods that are burned or overc o o ked. The c hemical is formed when compounds in these foods – water, sugar and amino acids – combine together when heated at high temperatur­es.

Scientists have shown that mice which had been fed large doses of acrylamide develop multiple tumours. And this led to the World Health Organisati­on labelling acrylamide as a ‘probable carcinogen’.

But according to the European Food Safety Authority, its ruling may be over-cautious.

First of all, there are many everyday substances that are considered a ‘probable carcinogen’, including hot drinks. The only confirmed l i nk between acrylamide and tumours is in animals alone.

And the amount of acrylamide seen to be harmful was the equivalent of eating at least 40 slices of burned toast per day, for a number of weeks.

Toxicology studies have shown that humans and rodents absorb acrylamide at different rates, and process it differentl­y.

One such study, from 2009, published in the journal Food And Chemical Toxicology, suggested that humans quickly process and excrete any acrylamide we eat, which protects against negative effects.

A 2015 Italian review of research, which examined links between acrylamide and 14 different types of cancer, found ‘no meaningful associatio­n’ with most cancer types, apart from a ‘modest associatio­n’ – and remember, this doesn’t equate to cause and effect – with kidney, endometria­l and ovarian cancers.

‘The evidence linking acrylamide to cancer is weak and inconsiste­nt,’ says Katie Parker, from Cancer Research UK.

‘ The l i kelihood of eating so much burnt toast that it significan­tly impacts on your cancer risk is very, very small.’

Coffee contains cancer-causing acrylamide – but only 1-2 micrograms per cup. Below 208 micrograms daily is safe.

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