The Mail on Sunday

NHS eyeing long-lasting jab to keep HIV at bay

- By Ethan Ennals

A JAB that offers long-lasting protection for people at a higher risk of catching HIV could soon be offered on the NHS.

The drug, cabotegrav­ir, which is administer­ed every two months, is an alternativ­e to the daily pills now given to at-risk groups to stop them contractin­g the virus which can lead to life-threatenin­g AIDS.

The UK’s Medicines and Healthcare Products Regulatory Agency concluded earlier this month that cabotegrav­ir could be offered as a preventati­ve treatment, and the NHS spending watchdog is now looking at whether it should fund the rollout of the £1,000-per-dose drug.

Each year in the UK there are about 4,000 new diagnoses of HIV, a sexually transmitte­d virus that damages immune cells.

Currently, people with an increased risk of an HIV infection – including HIV-negative men who have unprotecte­d sex with men or the partners of

‘It is well tolerated, causing fewer side effects than the daily pill’

people with HIV – are offered a daily pill known as pre-exposure prophylaxi­s (PrEP). The tablets block an enzyme in the body that HIV needs to spread. It costs about £40 for one month’s supply, and studies show it reduces the risk of infection by 99 per cent when taken every day.

But experts say the NHS should fund cabotegrav­ir, which blocks the same enzyme as PrEP, as many patients forget to take the tablets. Research suggests that around a fifth of people eligible for PrEP in the UK do not take it as instructed.

Dr John McSorley, a consultant sexual health expert at London North West University Healthcare NHS Trust, said: ‘Trials show cabotegrav­ir is really well tolerated, meaning it causes fewer side effects such as stomach pains. And it could benefit patients who struggle to remember to take PrEP.’

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