The Scotsman

Modern environmen­t blamed for 40% rise in children’s cancer cases

- By HARRIET LINE By JOHN VON RADOWITZ

The number of cancer cases in children has leapt by 40 per cent in less than two decades because of pollution, pesticides and gadgets, new analysis has shown.

There are 1,300 more diagnoses of the disease a year in people under the age of 25 compared to 1998 – costing the NHS £130 million extra a year.

Cases of colon cancer in children are up 200 per cent, while thyroid cancer cases have more than doubled.

Ovarian and cervical cancer cases have also seen stark rises – up by 70 per cent and 50 per cent respective­ly, analysis of ONS data by the charity Children with Cancer UK found.

Around 4,000 children and young people develop cancer each year and it is the leading cause of death in children aged one to 14 in the UK.

The 40 per cent jump in cases over 16 years is partially attributed to population growth, as the incidence rate per 100,000 people has risen by 30 per cent. However, Professor Denis Henshaw, scientific director at Children with Cancer UK, said that lifestyle and environmen­tal factors could have played a part in the rise.

“These significan­t rises in cancer cases cannot be explained by improvemen­ts in cancer diagnosis or registrati­on alone – lifestyle and environmen­tal causal factors must be considered.”

He said that burnt barbecues, the electric fields of power lines, and hairdriers were contributo­rs to the rise, as well as a pregnant woman’s diet and working shifts.

“We were shocked to see the figures,andit’sthemodern­lifestyle I’m afraid. Many items on the list of environmen­tal causes are now known to be carcinogen­ic, such as air pollution and pesticides and solvents.” He added: “What’s worrying is it is very hard to avoid a lot of these things. How can you avoid air pollution? It sometimes feels like we are fighting a losing battle.”

Children with Cancer UK are calling on the government and medical and science community to ensure children with cancer have access to precision medicine by 2020.

The charity is hosting a three-day internatio­nal conference on childhood cancer which begins today.

It will look at precision medicine, immunother­apy and influencea­ble causes of childhood cancer.

Precision medicine – which considers an individual’s genes, environmen­t and lifestyle to provide more targeted treatment – needs to be offered to all young people within the framework of clinical trials by 2020, the charity’s medical director has claimed. Injections of a “magic bullet” antibody drug may offer new hope to patients with life-threatenin­g asthma, studies suggest.

Benralizum­ab jabs prevented severe flare-ups of asthma which could no longer be controlled with high dose steroid inhalers and other drugs.

The drug targets and clears away rogue immune cells in the lungs called eosinophil­s that play a key role in allergies and asthma.

Two trials, Calima and Sirocco, compared the effects of benralizum­ab and a dummy placebo treatment in more than 2,500 patients with severe asthma.

Both found that the drug significan­tly reduced rates of “exacerbati­ons” – episodes of progressiv­ely-worsening shortness of breath, wheezing, and chest tightness. In the Calima trial exacerbati­ons were cut by 28-36 per cent.

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