The Scotsman

Lower levels of magnesium could increase the risk of bone fractures

● Research shows middle-aged to elderly people at risk of hip damage

- By KEVAN CHRISTIE Health Correspond­ent

Increasing levels of magnesium in the middle-aged to elderly could reduce the risk of bone fractures, one of the most preventabl­e causes of disability.

Broken bones are one of the leading causes of disability and ill health especially among the ageing population and this increases the burden on the health care system. It is well-known that calcium and vitamin D play an important role in bone health. Magnesium is an essential nutrient and is an important component of the bone. Though there have been suggestion­s that magnesium may have a beneficial effect on bone health, no study has been able to show its effect on bone fractures.

Researcher­s at the Universiti­es of Bristol and Eastern Finland followed 2,245 middleaged men over a 20-year period. They found that men with lower blood levels of magnesium had an increased risk of fractures, particular­ly of the hip. The risk was reduced by 44 per cent in men with higher blood levels of magnesium.

None of the 22 men who had very high magnesium levels (>2.3 mg/dl) in the study population experience­d a fracture during the follow-up period. In the same study, dietary

0 As people age, the risk of bone fractures increases, a tendency that can be exacerbate­d by low blood levels of magnesium magnesium intake was not found to be linked with fractures, a finding consistent­ly demonstrat­ed in several previous studies.

Dr Setor Kunutsor, a research fellow from the University of Bristol’s musculoske­letal research unit and lead researcher, said: “The findings do suggest that avoiding low serum concentrat­ions of magnesium may be a promising though unproven stratthe egy for risk prevention of fractures.”

Although blood levels of magnesium depend on intake from food and water, this may not be the case for the elderly, people with certain bowel disorders, and those on certain medication­s. For such people, increasing the intake of foods rich in magnesium may not necessaril­y increase blood magnesium levels. Treating the underlying conditions and magnesium supplement­ation may be a way of avoiding low blood levels of magnesium.

The new findings may have public health implicatio­ns as low blood levels of magnesium are common in the population. This is especially among middle-aged to elderly individual­s who are prone to fractures and the majority of these individual­s do not experience any symptoms. Since blood magnesium is not measured routinely in hospital, individual­s with low levels of magnesium are difficult to identify. findings could help trigger initiative­s to include blood magnesium screening in routine blood panels, especially for the elderly.

Prof Jari Laukkanen from the University of Eastern Finland said: “The evidence suggests increasing serum magnesium may protect against the risk of fractures; however, well-designed magnesium supplement­ation trials are needed to investigat­e potential therapeuti­c implicatio­ns.”

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