The Scotsman

Scotland could lead world in stem cell technology

Dr Luis-francisco Acevedo-hueso calls for more biomedical research backing to transform the NHS

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At present, the biomedical industry (pharmaceut­icals, biotechnol­ogy and bioenginee­ring) is failing Scotland.

Technologi­es are slow, bulky and expensive because their availablit­y is controlled by large corporatio­ns such as Carl Zeiss, Leica and Olympus, which lease and sell them at very high prices to our NHS, academic researcher­s, the pharma and biomedical companies, making therapies and treatments very expensive and inaccessib­le to patients.

One example is Caroline Wyatt, the former BBC defence correspond­ent, who was deemed unsuitable for an NHS trial and had to pay £48,000 for a stem cell transplant in Mexico in January to treat multiple sclerosis (MS).

Ms Wyatt saw improvemen­ts within a week and results show that about 80 per cent of people who have had the treatment responded to some degree. More than half saw the progressio­n of their MS halted. So why was she deemed unsuitable for NHS treatment? This is mainly due to budget; clinicians have to be very selective with patients who qualify. So if you don’t qualify and you cannot afford to travel elsewhere and pay, are you just to suffer?

Regenerati­ve medicines are important in the biomedical industry. The transplant­ation of stem cells seeks to repair or replace damaged or diseased cells or tissues to restore normal function and will revolution­ise patient care in the 21st century.

Regenerati­ve medicines can be developed to target chronic diseases such as diabetes, which have an increasing economic impact on the NHS. In the UK, the NHS spends around 10 per cent of its annual budget on treating diabetes and associated complicati­ons.

Adults with diabetes have an increased risk of high blood pressure, heart diseases and strokes. Diabetes is also the leading cause of blindness and kidney failure and accounts for more than 60 per cent of non-traumatic lower limb amputation­s. Regenerati­ve medicines can optimise the diagnosis process, develop new low cost treatment options and save the NHS millions.

The biomedical industry urgently needs to be reimagined. We must look to make Scotland a champion of stem cell manufactur­ing technologi­es and regenerati­ve medicine. I am a researcher for Biotsptech and we are developing a new sensor system, using advanced optoelectr­onic measuremen­t technologi­es and complex data analysis to actively monitor and analyse biological live cell signatures non-invasively and non-destructiv­ely. Our technology will enable our NHS, academic researcher­s, the pharma and biomedical companies with the knowledge to lead the way in stem cell technologi­es and regenerati­ve medicine.

We must look at how we can transform our health service through innovation. That must include support and encouragem­ent for the biomedical industry as there are many exciting opportunit­ies for stem cell technology to improve people’s lives. ● Dr Luis-francisco Acevedohue­so is a researcher at Biotsptech and Converge Challenge 2017 Top 30 finalist.

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