The Scotsman

Tiny patch that could revolution­ise treatment of Parkinson’s disease

- By MARK WAGHORN kevan.christie@jpress.co.uk

A futuristic device has been unveiled that could cure a variety of diseases – with a single touch.

The tiny patch – no bigger than a cufflink – is set to revolution­ise treatment of heart disease, stroke, Parkinson’s disease and other illnesses, say scientists.

Experiment­s on mice and pigs have been so successful the technique – which takes “a fraction of a second and is non-invasive” could be used on humans within months.

It works by injecting DNA into skin cells – switching their function to rescue failing organs in any part of the body. The technology – dubbed TNT (Tissue Nanotransf­ection) – may allow doctors to grow brain cells on a patient’s skin.

They could then harvest them and inject them into the brain to treat dementia or Parkinson’s.

In animals the technique turned skin cells into vascular cells – boosting blood flow and saving badly wounded legs.

The researcher­s were even able to grow brain cells on the skin surface of a mouse, harvest them and inject them into its injured brain.

Just a few weeks after having a stroke brain function was restored – and the mouse was healed.

The technique works by injecting skin cells with genetic code – proteins known as DNA or RNA – that changes them into other types of cells that can then be used to treat disease.

Dr Chandan Sen, a specialist in regenerati­ve medicine at Ohio State University, said: “By using our novel nanochip technology injured or compromise­d organs can be replaced.

“We have shown skin is a fertile land where we can grow the elements of any organ that is declining,”

Dr Sen added: “With this technology, we can convert skin cells into elements of any organ with just one touch.”

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