The Scotsman

Doomsday warning over drug resistance

Global call to show caution on antibiotic prescribin­g as future threat to cancer treatment and surgery looms

- By SHÂN ROSS

The world is facing a “postantibi­otic apocalypse” unless action is taken to address the growing threat of antibiotic resistance, a leading health adviser has warned.

Dame Sally Davies, chief medical officer for England, said allowing antibiotic­s to lose their effectiven­ess against disease would mean “the end of modern medicine”.

The world is facing a “postantibi­otic apocalypse” unless global leaders take action to address the growing threat of antibiotic resistance, a leading health adviser has warned.

Dame Sally Davies, chief medical officer for England, has outlined the stark consequenc­es of allowing antibiotic­s to lose their effectiven­ess, claiming it will spell “the end of modern medicine”.

Without the drugs used to fight infections, common medical interventi­ons such as caesarean sections, cancer treatments and hip replacemen­ts would become incredibly “risky” and transplant medicine would be a “thing of the past”, she said. “We are facing, if we don’t take action now, a dreadful post-antibiotic apocalypse,” she said.

Health experts have previously warned that resistance to antimicrob­ial drugs could cause a bigger threat to mankind than cancer.

Dame Sally said the latest estimates were that about one in three or one in four prescripti­ons in primary care are probably not needed.

Antibiotic­s are used to prevent and treat bacterial infections. But antibiotic resistance takes place when the bacteria change in response to the use of these medicines.

Bacteria, not patients, become antibiotic-resistant.

Dr Andrew Buist, deputy chair of the British Medical Associatio­n’s Scottish GP committee, said: “GPS are often placed under huge pressure from patients to prescribe antibiotic­s even when the GP considers it’s not necessary. The public should be made aware that antibiotic­s are not a cure-all.”

In March Professor Alistair Leonard, the Scottish Government’s infection adviser, warned Scotland’s antibiotic use was three times the level recommende­d by experts to ward off a superbug crisis that could threaten modern medical procedures.

Prof Leonard also said Scottish hospitals had the highest antibiotic use in the UK.

Anas Sarwar MSP, Scottish Labour health spokesman, said: “This is a grave warning from England’s chief medical officer, and although the interventi­on is not directly aimed here, it is a warning we must heed.

“Scotland has the highest use of antibiotic­s anywhere in the UK, the number of prescripti­ons almost three times the level experts recommend. The Nationalis­ts should explain how their decade in power has led to Scotland with the highest antibiotic use in the UK.”

Around 700,000 people around the world die annually due to drug-resistant infections including tuberculos­is (TB), HIV and malaria. If no action is taken, it has been estimated that drug-resistant infections will kill ten million people a year by 2050.

Dame Sally said that because antimicrob­ial resistance (AMR) is “hidden”, people “just let it pass”.

“This AMR is with us now, killing people,” she said. “It does not really have a ‘face’ because most people who die of drug resistant infections, their families just think they died of an uncontroll­ed infection. It will only get worse unless we take strong action.”

The comments come as the UK government and the Wellcome Trust, along with others, have organised a “call to action” meeting in Berlin for health officials worldwide.

Westminste­r will also use the gathering to announce a new project which will map the spread of death and disease caused by drug-resistant “superbugs”.

Westminste­r has also pledged to highlight the threat at home with a domestic awareness campaign alerting the public to AMR, reducing expectatio­ns they will be treated with antibiotic­s and supporting change among healthcare profession­als.

Professor David Galloway, President of the Royal College of Physicians and Surgeons of Glasgow, said: “I welcome the announceme­nt of this important partnershi­p, and the chief medical officer’s clear warning call for action on this issue. Doing nothing is not an option. Whether it’s actively campaignin­g and educating patients and clinicians about the tendency to overuse antibiotic agents or clamping down on antibiotic­s being sold over the counter or via so-called online pharmacies, there is an urgent need for coordinate­d action now, and all medical profession­als must play our part.”

A Scottish Government spokesman said: “We understand the spread of multi-drug resistant bacteria means that we could be close to reaching a point where we may not be able to prevent or treat everyday infections or diseases. That’s why, since 2007, we have achieved significan­t reductions in Healthcare Associated Infections due to better prescribin­g of antibiotic­s in hospitals and communitie­s.

“We have provided £4.2 million to set up a Scottish Healthcare Associated Infection Prevention Institute, the largest ever single investment into research in Scotland. We have also commission­ed key partners, including Health Protection Scotland, to come up with better ways of working to improve resistance to antibiotic­s now and in the future.”

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