The Scotsman

Rising use of common antihistam­ines linked to fertility problems in men

- By JENNIFER COCKERELL

Common allergy drugs have been linked to fertility problems in men.

Antihistam­ines are often used to relieve symptoms of allergies, such as hay fever, hives, conjunctiv­itis and reactions to insect bites or stings, and are available either over-the-counter or on prescripti­on.

An Argentine study found these commonly-taken drugs could have negative longterm side effects for male fertility.

The review, which is published in the journal Reproducti­on, found a number of studies reported adverse effects of antihistam­ine on normal testicular function.

They discovered antihistam­ines were likely to affect the production of male sexual hormones in the testicles, which could lead to altered morphology and decreased motil- ity of sperm, as well as a lower sperm count.

The researcher­s, who analysed a number of animal studies, said further research was needed as human studies were still very limited, but they cautioned against antihistam­ine overuse.

The rise in allergies in the industrial­ised world has led to an increased use of drugs such as antihistam­ines.

Histamine is a molecule produced by the body in response to an allergy.

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