The Scotsman

Russian vaccine trial sees antibodies form

- By KEVAN CHRISTIE

Preliminar­y results from Russian coronaviru­s vaccine trials have suggested the candidates saw no serious adverse events and that the jab also elicited an antibody response.

Results from two earlyphase non- randomised vaccine trials in a total of 76 people indicate that two formulatio­ns of a two- part vaccine have a good safety profile with no serious adverse events detected over 42 days.

The findings, published in The Lancet, also found the candidates induced an antibody response in all participan­ts within 21 days. Secondary outcomes from the trial suggest the vaccines also produce aT-cell response within 28 days.

The paper reports findings from two small phase 1- 2 trials lasting 42 days.

One looked at a frozen formulatio­n of the vaccine, and another involving al yo phil is ed( freezedrie­d) formulatio­n.

It is envisaged that the frozen formulatio­n will be for large- scale use, using existing global supply chains for vaccines.

The freeze- dried formulatio­n was developed for hard- to- reach regions as it is more stable and can be stored at 2C- 8C.

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